Neuroendocrinology of Affective Disorders

D. A. Gutman, C. B. Nemeroff

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Work during the past 50 years has highlighted the complex interplay between endocrine gland secretions and the central nervous system. This article provides a basic overview of the major hormone systems, including the hypothalamic-pituitary-adrenal axis, the thyroid axis, as well as growth hormone, prolactin, oxytocin, and vasopressin systems, with a focus on their relationship to affective disorders. Particular focus is on research identifying alterations in hormone availability (either excess or deficiency) and the relationship to mental illness.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier Ltd
Number of pages12
ISBN (Print)9780080450469
StatePublished - Jan 1 2009
Externally publishedYes


  • Anxiety
  • AVP
  • CRF
  • CRH
  • Depression
  • DST
  • Endocrine
  • GH
  • Growth hormone
  • Neuroendocrinology
  • Oxytocin
  • Thyroid
  • TRH
  • TSH

ASJC Scopus subject areas

  • Neuroscience(all)


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