Neuroanatomy and Neuroimaging of Anxiety Disorders

Jennifer C Britton, Scott L. Rauch

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Neuroimaging methods can be used to examine functional brain differences between healthy individuals and those with anxiety disorders. After the brain regions implicated in the pathophysiology of anxiety disorders (e.g., amygdalo-cortical circuitry) are reviewed, neuroimaging studies of posttraumatic stress disorder (PTSD), social anxiety disorder (SAD), specific phobia (SP), and panic disorder (PD) that report activations in these regions are discussed. Studies of obsessive-compulsive disorder (OCD) implicate a distinct neurocircuitry profile (i.e., corticostriatal- thalamic circuit) compared to the other anxiety disorders. Few neuroimaging studies of generalized anxiety disorder (GAD) have been conducted. In addition, results from functional connectivity analyses and the effects of treatment on neuroimaging findings are summarized.

Original languageEnglish
Title of host publicationOxford Handbook of Anxiety and Related Disorders
PublisherOxford University Press
ISBN (Print)9780199940141, 9780195307030
StatePublished - Sep 4 2008
Externally publishedYes


  • Amygdala
  • Cingulate
  • FMRI
  • Hippocampus
  • Insula
  • Medial prefrontal cortex
  • Neuroanatomy
  • Neurocircuitry
  • Neuroimaging

ASJC Scopus subject areas

  • Psychology(all)


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