Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans

R. Duara, A. Kushch, K. Gross-Glenn, W. W. Barker, B. Jallad, S. Pascal, David Loewenstein, J. Sheldon, M. Rabin, Bonnie Levin, H. Lubs

Research output: Contribution to journalArticle

197 Citations (Scopus)

Abstract

The areas of six bilateral brain segments in the right and left hemispheres, on a horizontal brain section, and the area of subdivisions of the corpus callosum, on a midsagittal brain section, were measured on magnetic resonance images obtained from 21 dyslexic and 29 control subjects. In the entire group, the frontal half of the horizontal brain section showed asymmetry, with the right side being larger, whereas posteriorly only the occipital polar segment was asymmetrical, with the left side being larger. Dyslexic subjects exhibited asymmetry, with the right side greater than the left side, in contrast to the relatively symmetrical pattern that is normally observed in the midposterior segment that corresponds to the angular gyrus. In the corpus callosum, dyslexic subjects were found to have a larger splenium than nondyslexic subjects, and dyslexic female subjects were found to have a larger splenium than dyslexic male subjects. Because transcallosal pathways connecting the left and right angular gyrus regions tranverse through the splenium of the corpus callosum, the above findings in dyslexic subjects suggest an anatomic abnormality in the angular gyrus region.

Original languageEnglish
Pages (from-to)410-416
Number of pages7
JournalArchives of Neurology
Volume48
Issue number4
StatePublished - Jan 1 1991

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Parietal Lobe
Corpus Callosum
Magnetic Resonance Imaging
Brain
Magnetic Resonance Spectroscopy
Dyslexics
Reader
Asymmetry

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Duara, R., Kushch, A., Gross-Glenn, K., Barker, W. W., Jallad, B., Pascal, S., ... Lubs, H. (1991). Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans. Archives of Neurology, 48(4), 410-416.

Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans. / Duara, R.; Kushch, A.; Gross-Glenn, K.; Barker, W. W.; Jallad, B.; Pascal, S.; Loewenstein, David; Sheldon, J.; Rabin, M.; Levin, Bonnie; Lubs, H.

In: Archives of Neurology, Vol. 48, No. 4, 01.01.1991, p. 410-416.

Research output: Contribution to journalArticle

Duara, R, Kushch, A, Gross-Glenn, K, Barker, WW, Jallad, B, Pascal, S, Loewenstein, D, Sheldon, J, Rabin, M, Levin, B & Lubs, H 1991, 'Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans', Archives of Neurology, vol. 48, no. 4, pp. 410-416.
Duara R, Kushch A, Gross-Glenn K, Barker WW, Jallad B, Pascal S et al. Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans. Archives of Neurology. 1991 Jan 1;48(4):410-416.
Duara, R. ; Kushch, A. ; Gross-Glenn, K. ; Barker, W. W. ; Jallad, B. ; Pascal, S. ; Loewenstein, David ; Sheldon, J. ; Rabin, M. ; Levin, Bonnie ; Lubs, H. / Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans. In: Archives of Neurology. 1991 ; Vol. 48, No. 4. pp. 410-416.
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