Neuro-rejuvenation for neuronal function

Yuan Liu, Richard K. Lee

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Neurodegenerative eye diseases, such as glaucoma, cause irreversible vision loss in millions of patients worldwide, creating serious medical, economic and social issues. Like other mammalian central nervous system tracts, optic nerve intrinsically lacks the capacity for axonal growth and its surrounding environment is also non-permissive to regeneration. Any axonal damage also triggers a vicious cycle of retinal ganglion cell (RGC) death. Exploring methods that can enhance RGCs survival and promote axonal regeneration will not only enable vision restoration for millions of patients, but also shed light on the treatment of other neurodegenerative diseases. In this review article, we will go through three current approaches to cure neurodegenerative eye diseases, including cell based therapy, neuro-regeneration and neuro-rejuvenation.

Original languageEnglish (US)
Pages (from-to)1560-1563
Number of pages4
JournalNeural Regeneration Research
Volume11
Issue number10
DOIs
StatePublished - Oct 2016

Keywords

  • Neuro-regeneration
  • Neuro-rejuvenation
  • Neurogenerative eye disease
  • Recovery of vision function
  • Stem cell therapy

ASJC Scopus subject areas

  • Developmental Neuroscience

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