Neural circuitry of judgment and decision mechanisms

Ioan Opris, Charles J. Bruce

Research output: Contribution to journalReview article

58 Citations (Scopus)

Abstract

Tracing the neural circuitry of decision formation is a critical step in the understanding of higher cognitive function. To make a decision, the primate brain coordinates dynamic interactions between several cortical and subcortical areas that process sensory, cognitive, and reward information. In selecting the optimal behavioral response, decision mechanisms integrate the accumulating evidence with reward expectation and knowledge from prior experience, and deliberate about the choice that matches the expected outcome. Linkages between sensory input and behavioral output responsible for response selection are shown in the neural activity of structures from the prefrontal-basal ganglia-thalamo-cortical loop. The deliberation process can be best described in terms of sensitivity, selection bias, and activation threshold. Here, we show a systems neuroscience approach of the visual saccade decision circuit and the interaction between its components during decision formation.

Original languageEnglish (US)
Pages (from-to)509-526
Number of pages18
JournalBrain Research Reviews
Volume48
Issue number3
DOIs
StatePublished - Jun 1 2005
Externally publishedYes

Fingerprint

Reward
Selection Bias
Saccades
Neurosciences
Basal Ganglia
Cognition
Primates
Brain

Keywords

  • Attention
  • Basal ganglia
  • Decision making
  • Executive function
  • Microstimulation
  • Neostriatum
  • Neural circuit
  • Neural system
  • Prefrontal cortex
  • Recording
  • Reward
  • Working memory

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Neural circuitry of judgment and decision mechanisms. / Opris, Ioan; Bruce, Charles J.

In: Brain Research Reviews, Vol. 48, No. 3, 01.06.2005, p. 509-526.

Research output: Contribution to journalReview article

Opris, Ioan ; Bruce, Charles J. / Neural circuitry of judgment and decision mechanisms. In: Brain Research Reviews. 2005 ; Vol. 48, No. 3. pp. 509-526.
@article{0f4709a06a61418d8dc8f9ff9ce647f5,
title = "Neural circuitry of judgment and decision mechanisms",
abstract = "Tracing the neural circuitry of decision formation is a critical step in the understanding of higher cognitive function. To make a decision, the primate brain coordinates dynamic interactions between several cortical and subcortical areas that process sensory, cognitive, and reward information. In selecting the optimal behavioral response, decision mechanisms integrate the accumulating evidence with reward expectation and knowledge from prior experience, and deliberate about the choice that matches the expected outcome. Linkages between sensory input and behavioral output responsible for response selection are shown in the neural activity of structures from the prefrontal-basal ganglia-thalamo-cortical loop. The deliberation process can be best described in terms of sensitivity, selection bias, and activation threshold. Here, we show a systems neuroscience approach of the visual saccade decision circuit and the interaction between its components during decision formation.",
keywords = "Attention, Basal ganglia, Decision making, Executive function, Microstimulation, Neostriatum, Neural circuit, Neural system, Prefrontal cortex, Recording, Reward, Working memory",
author = "Ioan Opris and Bruce, {Charles J.}",
year = "2005",
month = "6",
day = "1",
doi = "10.1016/j.brainresrev.2004.11.001",
language = "English (US)",
volume = "48",
pages = "509--526",
journal = "Brain Research Reviews",
issn = "0165-0173",
publisher = "Elsevier",
number = "3",

}

TY - JOUR

T1 - Neural circuitry of judgment and decision mechanisms

AU - Opris, Ioan

AU - Bruce, Charles J.

PY - 2005/6/1

Y1 - 2005/6/1

N2 - Tracing the neural circuitry of decision formation is a critical step in the understanding of higher cognitive function. To make a decision, the primate brain coordinates dynamic interactions between several cortical and subcortical areas that process sensory, cognitive, and reward information. In selecting the optimal behavioral response, decision mechanisms integrate the accumulating evidence with reward expectation and knowledge from prior experience, and deliberate about the choice that matches the expected outcome. Linkages between sensory input and behavioral output responsible for response selection are shown in the neural activity of structures from the prefrontal-basal ganglia-thalamo-cortical loop. The deliberation process can be best described in terms of sensitivity, selection bias, and activation threshold. Here, we show a systems neuroscience approach of the visual saccade decision circuit and the interaction between its components during decision formation.

AB - Tracing the neural circuitry of decision formation is a critical step in the understanding of higher cognitive function. To make a decision, the primate brain coordinates dynamic interactions between several cortical and subcortical areas that process sensory, cognitive, and reward information. In selecting the optimal behavioral response, decision mechanisms integrate the accumulating evidence with reward expectation and knowledge from prior experience, and deliberate about the choice that matches the expected outcome. Linkages between sensory input and behavioral output responsible for response selection are shown in the neural activity of structures from the prefrontal-basal ganglia-thalamo-cortical loop. The deliberation process can be best described in terms of sensitivity, selection bias, and activation threshold. Here, we show a systems neuroscience approach of the visual saccade decision circuit and the interaction between its components during decision formation.

KW - Attention

KW - Basal ganglia

KW - Decision making

KW - Executive function

KW - Microstimulation

KW - Neostriatum

KW - Neural circuit

KW - Neural system

KW - Prefrontal cortex

KW - Recording

KW - Reward

KW - Working memory

UR - http://www.scopus.com/inward/record.url?scp=19444387824&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=19444387824&partnerID=8YFLogxK

U2 - 10.1016/j.brainresrev.2004.11.001

DO - 10.1016/j.brainresrev.2004.11.001

M3 - Review article

VL - 48

SP - 509

EP - 526

JO - Brain Research Reviews

JF - Brain Research Reviews

SN - 0165-0173

IS - 3

ER -