Nerve crossover techniques for urinary bladder reinnervation: Animal and human cadaver studies

B. Vorstman, S. Schlossberg, H. Landy, L. Kass

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Interruption of spinal pathways integrating central and peripheral bladder control mechanisms will result in neurogenic bladder dysfunction. If central pathways could be restored to the decentralized bladder through a microneural reconstructive technique a return of useful function might be achieved. This anatomical study describes the nerve crossover techniques used in human cadaver dissections for connecting intercostal nerves to sacral roots intraspinally. The techniques were modified from and compared to similar procedures used in an animal model where adjacent extradural roots were connected through a nerve graft. We have shown previously that the unilaterally decentralized bladder of the cat can be recentralized after a nerve crossover procedure. If additional laboratory studies can document return of useful bladder function we anticipate that selected patients may benefit from similar nerve crossover techniques to bypass a spinal cord lesion to recentralize the bladder.

Original languageEnglish (US)
Pages (from-to)1043-1047
Number of pages5
JournalJournal of Urology
Volume137
Issue number5
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Urology

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