Neonatal gastrointestinal stromal tumor. Report of a case and review of literature

Bita Geramizadeh, Ali Bahador, Parvin Ganjei-Azar, Ali Asadi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the reported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6-day-old female neonate presenting with lethargy, poor feeding, constipation, abdominal distention, and rectal bleeding. She was operated on with the impression of intestinal obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well-defined and round 3-cm mass in the cecal area. Diagnosis was made by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c-kit but negative for all other markers (desmin, actin, S100, NSE, and CD-34). So the case was an undifferentiated GIST. After 1 year of follow-up the patient was completely normal.

Original languageEnglish
Pages (from-to)572-574
Number of pages3
JournalJournal of Pediatric Surgery
Volume40
Issue number3
DOIs
StatePublished - Mar 1 2005

Fingerprint

Gastrointestinal Stromal Tumors
Lethargy
Desmin
Intestinal Obstruction
Vimentin
Constipation
Actins
Newborn Infant
Hemorrhage
Neoplasms

Keywords

  • Gastrointestinal stromal tumor
  • Neonate
  • Undifferentiated

ASJC Scopus subject areas

  • Surgery

Cite this

Neonatal gastrointestinal stromal tumor. Report of a case and review of literature. / Geramizadeh, Bita; Bahador, Ali; Ganjei-Azar, Parvin; Asadi, Ali.

In: Journal of Pediatric Surgery, Vol. 40, No. 3, 01.03.2005, p. 572-574.

Research output: Contribution to journalArticle

Geramizadeh, Bita ; Bahador, Ali ; Ganjei-Azar, Parvin ; Asadi, Ali. / Neonatal gastrointestinal stromal tumor. Report of a case and review of literature. In: Journal of Pediatric Surgery. 2005 ; Vol. 40, No. 3. pp. 572-574.
@article{50f474e2c0964aa3836ab600346ef20c,
title = "Neonatal gastrointestinal stromal tumor. Report of a case and review of literature",
abstract = "Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the reported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6-day-old female neonate presenting with lethargy, poor feeding, constipation, abdominal distention, and rectal bleeding. She was operated on with the impression of intestinal obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well-defined and round 3-cm mass in the cecal area. Diagnosis was made by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c-kit but negative for all other markers (desmin, actin, S100, NSE, and CD-34). So the case was an undifferentiated GIST. After 1 year of follow-up the patient was completely normal.",
keywords = "Gastrointestinal stromal tumor, Neonate, Undifferentiated",
author = "Bita Geramizadeh and Ali Bahador and Parvin Ganjei-Azar and Ali Asadi",
year = "2005",
month = "3",
day = "1",
doi = "10.1016/j.jpedsurg.2004.11.031",
language = "English",
volume = "40",
pages = "572--574",
journal = "Journal of Pediatric Surgery",
issn = "0022-3468",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Neonatal gastrointestinal stromal tumor. Report of a case and review of literature

AU - Geramizadeh, Bita

AU - Bahador, Ali

AU - Ganjei-Azar, Parvin

AU - Asadi, Ali

PY - 2005/3/1

Y1 - 2005/3/1

N2 - Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the reported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6-day-old female neonate presenting with lethargy, poor feeding, constipation, abdominal distention, and rectal bleeding. She was operated on with the impression of intestinal obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well-defined and round 3-cm mass in the cecal area. Diagnosis was made by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c-kit but negative for all other markers (desmin, actin, S100, NSE, and CD-34). So the case was an undifferentiated GIST. After 1 year of follow-up the patient was completely normal.

AB - Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the reported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6-day-old female neonate presenting with lethargy, poor feeding, constipation, abdominal distention, and rectal bleeding. She was operated on with the impression of intestinal obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well-defined and round 3-cm mass in the cecal area. Diagnosis was made by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c-kit but negative for all other markers (desmin, actin, S100, NSE, and CD-34). So the case was an undifferentiated GIST. After 1 year of follow-up the patient was completely normal.

KW - Gastrointestinal stromal tumor

KW - Neonate

KW - Undifferentiated

UR - http://www.scopus.com/inward/record.url?scp=15744401199&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15744401199&partnerID=8YFLogxK

U2 - 10.1016/j.jpedsurg.2004.11.031

DO - 10.1016/j.jpedsurg.2004.11.031

M3 - Article

C2 - 15793738

AN - SCOPUS:15744401199

VL - 40

SP - 572

EP - 574

JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

SN - 0022-3468

IS - 3

ER -