Neonatal gastrointestinal stromal tumor. Report of a case and review of literature

Bita Geramizadeh, Ali Bahador, Parvin Ganjei-Azar, Ali Asadi

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12 Scopus citations


Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the reported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6-day-old female neonate presenting with lethargy, poor feeding, constipation, abdominal distention, and rectal bleeding. She was operated on with the impression of intestinal obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well-defined and round 3-cm mass in the cecal area. Diagnosis was made by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c-kit but negative for all other markers (desmin, actin, S100, NSE, and CD-34). So the case was an undifferentiated GIST. After 1 year of follow-up the patient was completely normal.

Original languageEnglish (US)
Pages (from-to)572-574
Number of pages3
JournalJournal of Pediatric Surgery
Issue number3
StatePublished - Mar 2005


  • Gastrointestinal stromal tumor
  • Neonate
  • Undifferentiated

ASJC Scopus subject areas

  • Surgery


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