Neighboring-group participation in the hydrolysis of coordinated nitriles

Robert J. Balahura, W. L. Purcell

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Abstract

The hydrolysis reaction (Chemical Equation Presented) has been studied. For R = CN, kh = 1050 ± 60 M-1 s-1, ΔH‡ = 13.6 ± 0.5 kcal mol-1, ΔS‡ = 1.0 ± 2 eu at 25°C, and I = 1.0 M (LiClO4). For R = CONH2, kh = (5.8 ± 0.5) × 106 M-1 s-1, ΔH‡ = 21.3 ± 0.5 kcal mol-1, ΔS‡ = 44 ± 2 eu at 25°C, and I = 1.0 M (LiClO4). The unusual kinetic parameters for the latter complex are attributed to neighboring-group participation by the amide group.

Original languageEnglish
Pages (from-to)4159-4163
Number of pages5
JournalInorganic Chemistry
Volume20
Issue number12
StatePublished - Dec 1 1981

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ASJC Scopus subject areas

  • Inorganic Chemistry

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Balahura, R. J., & Purcell, W. L. (1981). Neighboring-group participation in the hydrolysis of coordinated nitriles. Inorganic Chemistry, 20(12), 4159-4163.