Necrotizing enterocolitis in full-term or near-term infants

Risk factors

Emilia Marlinez-Tallo, Nelson R Claure, Eduardo Bancalari

Research output: Contribution to journalArticle

102 Citations (Scopus)

Abstract

A retrospective case-control study of necrotizing enterocolitis (NEC) affecting infants weighing > 2000 g at birth was performed to determine those factors which could contribute to the development of NEC. Twenty-four infants met the criteria of definite NEC. For each case the next 2 healthy newborns were matched as controls. When compared with the control group, NEC infants had a significantly higher frequency of prolonged rupture of membranes, chorioamnionitis, Apgar score < 7 at 1 and 5 min, respiratory problems, congenital heart disease, hypoglycemia, and exchange transfusions. Only 3 infants with NEC were healthy newborns with an unremarkable perinatal course before NEC. There were no differences in the frequency of preeclampsia, maternal diabetes, maternal drug abuse, meconium-stained amniotic fluid and polycythemia. These results indicate that most of these more mature infants have a predisposing factor before developing NEC.

Original languageEnglish
Pages (from-to)292-298
Number of pages7
JournalBiology of the Neonate
Volume71
Issue number5
StatePublished - Jun 4 1997

Fingerprint

Necrotizing Enterocolitis
Mothers
Newborn Infant
Chorioamnionitis
Meconium
Polycythemia
Apgar Score
Amniotic Fluid
Pre-Eclampsia
Hypoglycemia
Causality
Substance-Related Disorders
Case-Control Studies
Rupture
Heart Diseases
Parturition
Control Groups
Membranes

Keywords

  • Necrotizing enterocolitis
  • Pseudomembranous enterocolitis

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Necrotizing enterocolitis in full-term or near-term infants : Risk factors. / Marlinez-Tallo, Emilia; Claure, Nelson R; Bancalari, Eduardo.

In: Biology of the Neonate, Vol. 71, No. 5, 04.06.1997, p. 292-298.

Research output: Contribution to journalArticle

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