Necrobiotic xanthogranuloma associated with a benign monoclonal gammopathy

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16 Scopus citations

Abstract

Necrobiotic xanthogranuloma (NXG) is a disorder characterized by indurated, yellow-red nodules or plaques, primarily involving the face and, less frequently, the trunk and extremities. NXG may be associated with paraproteinemia, multiple myeloma, and hypertension. Histologically, xanthogranulomatous features with hyaline necrosis or necrobiosis are present. No first-line treatment has been established. This disease is a chronic process, and a patient's prognosis depends on the degree of extracutaneous involvement and the presence of visceral malignancies. We describe a patient with typical cutaneous and histologic findings of NXG with an associated monoclonal gammopathy.

Original languageEnglish (US)
Pages (from-to)47-50
Number of pages4
JournalCutis
Volume72
Issue number1
StatePublished - Jul 1 2003

ASJC Scopus subject areas

  • Dermatology

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