Nasopharyngeal angiofibromas: Staging and management

James R. Chandler, Lee Moskowitz, Richard Goulding, Robert M. Quencer

Research output: Contribution to journalArticlepeer-review

174 Scopus citations


We propose a system for staging nasopharyngeal angiofibromas based on clinical evaluation and computerized tomography. Twenty-three patients with this pathologic diagnosis have been managed at the University of Miami/Jackson Memorial Medical Center in the past two decades. In 13 patients, the clinical diagnosis was confirmed by transnasal biopsy as a minor outpatient procedure. This avoided unnecessary diagnostic studies, shortened the hospital stay, and expedited treatment. Computerized tomography has replaced conventional x-ray studies and routine tomography, although angiography is still necessary for proper evaluation of larger tumors. Stage groupings recommended on the basis of this experience are stage I - tumor confined to nasopharynx; stage II - tumor extending into nasal cacity and/or sphenoid sinus; Stage III - tumor extending into one or more of the following: antrum, ethmoid sinus, pterygomaxillary and infratemporal fossae, orbit, and/or cheek; and stage IV - tumor extending into cranial cavity. Surgical excision is recommended for stages I, II, and III. Stage IV tumors require surgical resection and/or radiation therapy with the possible addition of hormonal therapy.

Original languageEnglish (US)
Pages (from-to)322-329
Number of pages8
JournalAnnals of Otology, Rhinology & Laryngology
Issue number4
StatePublished - Jul 1984

ASJC Scopus subject areas

  • Otorhinolaryngology


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