Nanoscale bio-molecular control using EC-OWLS

J. P. Bearineer, J. Vörös, J. A. Hubbell, M. Textor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A recently developed technique termed "Electrochemical Optical Waveguide Lightmode Spectroscopy" (EC-OWLS) combines evanescent-field optical sensing with electrochemical control of surface adsorption processes. Initial EC-OWLS investigations efficiently monitored molecular surface adsorption and layer thickness changes of an adsorbed polymer layer examined in situ as a function of potential applied to a waveguide1. A layer of indium tin oxide (ITO) served as both a high retractive index waveguide for optical sensing, and a conductive electrode; an electrochemical flow-through fluid cell incorporated working, reference and counter electrodes. Poly(L-lysine)-grafted-poly(ethylene glycol) (PLL-g-PEG) served as a model, polycation adsorbate. Results indicate that adsorption and desorption of PLL-g-PEG from aqueous buffer are a function of applied potential, and that binding events subsequent to PLL-g-PEG functionalization are dependent on reorganization in the molecular adlayer.

Original languageEnglish
Title of host publication2003 Nanotechnology Conference and Trade Show - Nanotech 2003
EditorsM. Laudon, B. Romanowicz
Pages48-51
Number of pages4
Volume1
StatePublished - Dec 1 2003
Externally publishedYes
Event2003 Nanotechnology Conference and Trade Show - Nanotech 2003 - San Francisco, CA, United States
Duration: Feb 23 2003Feb 27 2003

Other

Other2003 Nanotechnology Conference and Trade Show - Nanotech 2003
CountryUnited States
CitySan Francisco, CA
Period2/23/032/27/03

Fingerprint

Optical waveguides
Polyethylene glycols
Spectroscopy
Adsorption
Evanescent fields
Electrodes
Adsorbates
Tin oxides
Indium
Desorption
Waveguides
Fluids
Polymers

Keywords

  • Adsorption
  • Biosensor
  • Electrical potential
  • Indium tin oxide (ito)
  • Polyionic polymers publication searches and indexing

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Bearineer, J. P., Vörös, J., Hubbell, J. A., & Textor, M. (2003). Nanoscale bio-molecular control using EC-OWLS. In M. Laudon, & B. Romanowicz (Eds.), 2003 Nanotechnology Conference and Trade Show - Nanotech 2003 (Vol. 1, pp. 48-51)

Nanoscale bio-molecular control using EC-OWLS. / Bearineer, J. P.; Vörös, J.; Hubbell, J. A.; Textor, M.

2003 Nanotechnology Conference and Trade Show - Nanotech 2003. ed. / M. Laudon; B. Romanowicz. Vol. 1 2003. p. 48-51.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bearineer, JP, Vörös, J, Hubbell, JA & Textor, M 2003, Nanoscale bio-molecular control using EC-OWLS. in M Laudon & B Romanowicz (eds), 2003 Nanotechnology Conference and Trade Show - Nanotech 2003. vol. 1, pp. 48-51, 2003 Nanotechnology Conference and Trade Show - Nanotech 2003, San Francisco, CA, United States, 2/23/03.
Bearineer JP, Vörös J, Hubbell JA, Textor M. Nanoscale bio-molecular control using EC-OWLS. In Laudon M, Romanowicz B, editors, 2003 Nanotechnology Conference and Trade Show - Nanotech 2003. Vol. 1. 2003. p. 48-51
Bearineer, J. P. ; Vörös, J. ; Hubbell, J. A. ; Textor, M. / Nanoscale bio-molecular control using EC-OWLS. 2003 Nanotechnology Conference and Trade Show - Nanotech 2003. editor / M. Laudon ; B. Romanowicz. Vol. 1 2003. pp. 48-51
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