Nail-patella syndrome: Clinical clues for making the diagnosis

Alexandra Price, Jessica Cervantes, Scott Lindsey, Divya Aickara, Shasa Hu

Research output: Contribution to journalArticle

Abstract

Nail-patella syndrome (NPS) is a rare autosomal-dominant disorder characterized by the classic triad of fingernail dysplasia, patellar absence/hypoplasia, and presence of iliac horns. We describe the various features of NPS, focusing on dermatologic and musculoskeletal findings. A 69-year-old man presented to the dermatology clinic for a routine skin cancer screening. Physical examination revealed hypoplastic fingernails with longitudinal ridging, splitting, and triangular lunulae; left patellar absence and right patellar hypoplasia; and bilateral iliac horns that had been present since birth. His medical history was remarkable for glaucoma, hypertension, osteoporosis, and chronic kidney disease. A detailed awareness of the classic findings of NPS can facilitate its early recognition and enable appropriate treatment and longterm screening.

Original languageEnglish (US)
Pages (from-to)126-129
Number of pages4
JournalCutis
Volume101
Issue number2
StatePublished - Feb 1 2018

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ASJC Scopus subject areas

  • Dermatology

Cite this

Price, A., Cervantes, J., Lindsey, S., Aickara, D., & Hu, S. (2018). Nail-patella syndrome: Clinical clues for making the diagnosis. Cutis, 101(2), 126-129.