Nail-patella syndrome

Clinical clues for making the diagnosis

Alexandra Price, Jessica Cervantes, Scott Lindsey, Divya Aickara, Shasa Hu

Research output: Contribution to journalArticle

Abstract

Nail-patella syndrome (NPS) is a rare autosomal-dominant disorder characterized by the classic triad of fingernail dysplasia, patellar absence/hypoplasia, and presence of iliac horns. We describe the various features of NPS, focusing on dermatologic and musculoskeletal findings. A 69-year-old man presented to the dermatology clinic for a routine skin cancer screening. Physical examination revealed hypoplastic fingernails with longitudinal ridging, splitting, and triangular lunulae; left patellar absence and right patellar hypoplasia; and bilateral iliac horns that had been present since birth. His medical history was remarkable for glaucoma, hypertension, osteoporosis, and chronic kidney disease. A detailed awareness of the classic findings of NPS can facilitate its early recognition and enable appropriate treatment and longterm screening.

Original languageEnglish (US)
Pages (from-to)126-129
Number of pages4
JournalCutis
Volume101
Issue number2
StatePublished - Feb 1 2018

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Nail-Patella Syndrome
Horns
Nails
Skin Neoplasms
Dermatology
Chronic Renal Insufficiency
Early Detection of Cancer
Glaucoma
Osteoporosis
Physical Examination
Parturition
Hypertension
Therapeutics

ASJC Scopus subject areas

  • Dermatology

Cite this

Price, A., Cervantes, J., Lindsey, S., Aickara, D., & Hu, S. (2018). Nail-patella syndrome: Clinical clues for making the diagnosis. Cutis, 101(2), 126-129.

Nail-patella syndrome : Clinical clues for making the diagnosis. / Price, Alexandra; Cervantes, Jessica; Lindsey, Scott; Aickara, Divya; Hu, Shasa.

In: Cutis, Vol. 101, No. 2, 01.02.2018, p. 126-129.

Research output: Contribution to journalArticle

Price, A, Cervantes, J, Lindsey, S, Aickara, D & Hu, S 2018, 'Nail-patella syndrome: Clinical clues for making the diagnosis', Cutis, vol. 101, no. 2, pp. 126-129.
Price A, Cervantes J, Lindsey S, Aickara D, Hu S. Nail-patella syndrome: Clinical clues for making the diagnosis. Cutis. 2018 Feb 1;101(2):126-129.
Price, Alexandra ; Cervantes, Jessica ; Lindsey, Scott ; Aickara, Divya ; Hu, Shasa. / Nail-patella syndrome : Clinical clues for making the diagnosis. In: Cutis. 2018 ; Vol. 101, No. 2. pp. 126-129.
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