Nail involvement in autoimmune bullous disorders

Antonella Tosti, Marisa André, Dédée F. Murrell

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Autoimmune bullous disorders frequently cause nail abnormalities, particularly paronychia and onychomadesis. In pemphigus vulgaris (PV) nail abnormalities can even precede skin findings. Nail lesions often relapse just before generalized disease exacerbation or recurrence. Severe nail changes are often associated with extensive and severe disease. Fingernails are more commonly affected. A report in the literature associates hemorrhagic nail abnormalities with poor prognosis in patients with PV. Nail scarring and pterygium are a rare complication of bullous pemphigoid. Nail loss has been occasionally reported in epidermolysis bullosa acquisita.

Original languageEnglish (US)
Pages (from-to)511-513
Number of pages3
JournalDermatologic Clinics
Volume29
Issue number3
DOIs
StatePublished - Jul 1 2011

Keywords

  • Bullous pemphigoid
  • Onycholysis
  • Onychomadesis
  • Paronychia
  • Pemphigus vulgaris
  • Pterygium

ASJC Scopus subject areas

  • Dermatology

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