Nail changes as the first sign of systemic amyloidosis

P. A. Fanti; A. Tosti; R. Morelli; G. Galbiati

doi:10.1159/000247630

Nail changes as the first sign of systemic amyloidosis

P. A. Fanti, A. Tosti, R. Morelli, G. Galbiati

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

A 68-year-old man had had for 3 years a severe onychodystrophy involving all fingers and toes which clinically mimicked nail lichen planus. The nail biopsy showed amyloid deposits in the superficial dermis of the nail matrix. Physical, pathological and laboratory examinations confirmed the diagnosis of primary systemic amyloidosis. At the time of the diagnosis the patient did not present any other cutaneous sign of systemic amyloidosis.

Original language	English (US)
Pages (from-to)	44-46
Number of pages	3
Journal	Dermatologica
Volume	183
Issue number	1
DOIs	https://doi.org/10.1159/000247630
State	Published - 1991
Externally published	Yes

Keywords

amyloid deposits
histopathology
nail changes
systemic amyloidosis

ASJC Scopus subject areas

Dermatology

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abstract = "A 68-year-old man had had for 3 years a severe onychodystrophy involving all fingers and toes which clinically mimicked nail lichen planus. The nail biopsy showed amyloid deposits in the superficial dermis of the nail matrix. Physical, pathological and laboratory examinations confirmed the diagnosis of primary systemic amyloidosis. At the time of the diagnosis the patient did not present any other cutaneous sign of systemic amyloidosis.",

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AB - A 68-year-old man had had for 3 years a severe onychodystrophy involving all fingers and toes which clinically mimicked nail lichen planus. The nail biopsy showed amyloid deposits in the superficial dermis of the nail matrix. Physical, pathological and laboratory examinations confirmed the diagnosis of primary systemic amyloidosis. At the time of the diagnosis the patient did not present any other cutaneous sign of systemic amyloidosis.

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KW - histopathology

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Nail changes as the first sign of systemic amyloidosis

Abstract

Keywords

ASJC Scopus subject areas

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