Myocarditis and ARVC/D

Variants or mimics?

Tanyanan Tanawuttiwat, Solomon J. Sager, Joshua Hare, Robert J Myerburg

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a disease characterized by fibrofatty replace- ment of the right ventricular (RV) myocardium, which is generally considered to be based on variations in desmo-somal genes. However, its pathogenes is is not completely clear since myocarditis and high-intensity athletics have both been postulated to contribute to the onset and progression of the disease pattern. We observeda 21-year-old woman who presented with fulminant lymphocytic myocarditisand subsequently fulfilled the diagnostic criteria for ARVC/D by imaging and electro cardiographic characteristics after complete resolution of left ventricular(LV) abnormalities associated with myo carditis. None of the known common mutations associated with ARVC/D were identified in this patient. This report supports the hypothesis of a common pathophysiology of ARVC/D associated with desmosomal dysfunction, which can be based on genetic predisposition or acquired injury.

Original languageEnglish
Pages (from-to)1544-1548
Number of pages5
JournalHeart Rhythm
Volume10
Issue number10
DOIs
StatePublished - Oct 1 2013

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Arrhythmogenic Right Ventricular Dysplasia
Myocarditis
Genetic Predisposition to Disease
Sports
Disease Progression
Myocardium
Mutation
Wounds and Injuries
Genes

Keywords

  • Arrhythmoge nicright ventricular cardiomyopathy
  • Myocarditis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Myocarditis and ARVC/D : Variants or mimics? / Tanawuttiwat, Tanyanan; Sager, Solomon J.; Hare, Joshua; Myerburg, Robert J.

In: Heart Rhythm, Vol. 10, No. 10, 01.10.2013, p. 1544-1548.

Research output: Contribution to journalArticle

Tanawuttiwat, Tanyanan ; Sager, Solomon J. ; Hare, Joshua ; Myerburg, Robert J. / Myocarditis and ARVC/D : Variants or mimics?. In: Heart Rhythm. 2013 ; Vol. 10, No. 10. pp. 1544-1548.
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