Myoblasts are aligned with collagen fibrils in regenerating frog tadpole tails

Robert H. Warren

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Myoblasts in the regenerating frog tadpole tail differentiate from mesen chymal cells that lie next to the basement membrane of the epidermis of the tail. As these cells elongate and form myotubes, they orientate uniformly in the longitudinal axis of the tail. The collagen fibrils of the basement membrane adjacent to the myogenic cells are also orientated in the tail axis just prior to and during the time when the myogenic cells are elongating. This has been demonstrated by transmission electron microscopy of thin sections, by differential interference contrast microscopy of isolated basement membranes, and by scanning electron microscopy of the inner surface of the basement membrane. Since elongating myoblasts are in contact with the longitudinally orientated fibrils, the latter could provide directional cues to the elongating myoblasts. This proposition is supported by the finding that isolated basement membranes readily orientate cells that are cultured upon their inner surfaces.

Original languageEnglish
Pages (from-to)773-785
Number of pages13
JournalTissue and Cell
Volume13
Issue number4
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

Fingerprint

myoblasts
Myoblasts
basement membrane
tadpoles
Basement Membrane
Anura
Larva
collagen
frogs
tail
Collagen
cells
Interference Microscopy
epidermis (animal)
Skeletal Muscle Fibers
Transmission Electron Microscopy
Epidermis
Electron Scanning Microscopy
Cues
transmission electron microscopy

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Insect Science

Cite this

Myoblasts are aligned with collagen fibrils in regenerating frog tadpole tails. / Warren, Robert H.

In: Tissue and Cell, Vol. 13, No. 4, 01.01.1981, p. 773-785.

Research output: Contribution to journalArticle

Warren, Robert H. / Myoblasts are aligned with collagen fibrils in regenerating frog tadpole tails. In: Tissue and Cell. 1981 ; Vol. 13, No. 4. pp. 773-785.
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