Mycobacterium kansasii pulmonary infection in patients with AIDS: Spectrum of chest radiographic findings

Joel Fishman, David S. Schwartz, Gerard J. Sais

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

PURPOSE: To determine the chest radiographic findings and clinical manifestations of Mycobacterium kansasii pulmonary infection in patients with acquired immunodeficiency syndrome (AIDS). MATERIALS AND METHODS: Criteria for diagnosis included two or more positive cultures from respiratory sources, pulmonary symptoms or fever, and no other identifiable cause of pulmonary disease. Chest radiographs at initial examination and follow-up were evaluated for parenchymal opacities, cavitation, adenopathy, and pleural effusions. Medical records were reviewed for clinical signs and symptoms, CD4 cell count, presence of additional pathogens, and response to antimycobacterial therapy. RESULTS: Of 96 patients, 16 (17%) satisfied all criteria for M kansasii pulmonary infection. The mean CD4 cell count was 24/mm3. Twelve patients (75%) demonstrated alveolar opacities, only three (19%) of which were cavitary. Interstitial opacities (6%) and pleural effusions (12%) were uncommon. Four (25%) patients had thoracic lymphadenopathy, which was the only positive radiographic finding in two patients. Fourteen patients were treated for M kansasii, and 10 (71%) showed clinical and radiographic improvement. CONCLUSION: Patients with AIDS and pulmonary M kansasii frequently demonstrate focal alveolar opacities. Symptomatic patients with pulmonary nontuberculous mycobacteria should be presumptively treated for pulmonary M kansasii until final culture results are available.

Original languageEnglish
Pages (from-to)171-175
Number of pages5
JournalRadiology
Volume204
Issue number1
StatePublished - Jul 1 1997

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Mycobacterium kansasii
Acquired Immunodeficiency Syndrome
Thorax
Lung
Infection
Pleural Effusion
CD4 Lymphocyte Count
Nontuberculous Mycobacteria
Lung Diseases
Signs and Symptoms
Medical Records
Fever

Keywords

  • Acquired immunodeficiency syndrome (AIDS)
  • Lung, infection
  • Mycobacteria
  • Tuberculosis, pulmonary

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Mycobacterium kansasii pulmonary infection in patients with AIDS : Spectrum of chest radiographic findings. / Fishman, Joel; Schwartz, David S.; Sais, Gerard J.

In: Radiology, Vol. 204, No. 1, 01.07.1997, p. 171-175.

Research output: Contribution to journalArticle

Fishman, Joel ; Schwartz, David S. ; Sais, Gerard J. / Mycobacterium kansasii pulmonary infection in patients with AIDS : Spectrum of chest radiographic findings. In: Radiology. 1997 ; Vol. 204, No. 1. pp. 171-175.
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