Musculoskeletal manifestations of paget's disease of bone

Roy D. Altman, Barbara Collins

Research output: Contribution to journalArticle

92 Scopus citations

Abstract

A review of 290 patients with Paget's disease of bone revealed 83% had one or more rheumatic syndromes. The most common finding was back pain (37%), most often related to an independent osteoarthritic process or Paget's disease precipitating or complicating spinal osteoarthritis. Paget's disease as a sole source of back pain was distinctly uncommon (2%). Osteoarthritis related to Paget's disease was present in the hip (30%) and knee (11%). Paget's disease in spondylitis was present in 4 patients and in ankylosing hyperostosis in 4 patients. The latter group had very active Paget's disease. Rheumatoid arthritis (1%), hyperuricemia (20%), and gout (4%) did not appear increased in this group.

Original languageEnglish (US)
Pages (from-to)1121-1127
Number of pages7
JournalArthritis & Rheumatism
Volume23
Issue number10
DOIs
StatePublished - Oct 1980

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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