Muscle fibre size in normal infants, children and adolescents. An autopsy study

W. Aherne; D. R. Ayyar; P. A. Clarke; J. N. Walton

doi:10.1016/0022-510X(71)90085-2

Muscle fibre size in normal infants, children and adolescents. An autopsy study

W. Aherne, D. R. Ayyar, P. A. Clarke, J. N. Walton

Neurology

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

The results are reported of measurements of muscle fibre size, area and diameter in specimens of limb muscle obtained at autopsy from infants and children dying from acute infective illness or as a result of trauma. All observations were carried out upon transverse sections of paraffin-embedded muscle from deltoid, biceps brachii, rectus femoris and gastrocnemius; the results are analysed and are related to body height and growth. There is a steady increase in muscle fibre diameter and area with increasing body size for each muscle examined and we provide figures against which changes in abnormal muscle can be compared.

Original language	English (US)
Pages (from-to)	171-182
Number of pages	12
Journal	Journal of the Neurological Sciences
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/0022-510X(71)90085-2
State	Published - Oct 1971

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1016/0022-510X(71)90085-2

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title = "Muscle fibre size in normal infants, children and adolescents. An autopsy study",

abstract = "The results are reported of measurements of muscle fibre size, area and diameter in specimens of limb muscle obtained at autopsy from infants and children dying from acute infective illness or as a result of trauma. All observations were carried out upon transverse sections of paraffin-embedded muscle from deltoid, biceps brachii, rectus femoris and gastrocnemius; the results are analysed and are related to body height and growth. There is a steady increase in muscle fibre diameter and area with increasing body size for each muscle examined and we provide figures against which changes in abnormal muscle can be compared.",

author = "W. Aherne and Ayyar, {D. R.} and Clarke, {P. A.} and Walton, {J. N.}",

note = "Funding Information: This stud/,' was aided by grants from the Muscular Dystrophy Associations of America, Inc., the Muscular Dystrophy Group of Great Britain and the Medical Research Council.",

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AU - Aherne, W.

AU - Ayyar, D. R.

AU - Clarke, P. A.

AU - Walton, J. N.

N1 - Funding Information: This stud/,' was aided by grants from the Muscular Dystrophy Associations of America, Inc., the Muscular Dystrophy Group of Great Britain and the Medical Research Council.

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N2 - The results are reported of measurements of muscle fibre size, area and diameter in specimens of limb muscle obtained at autopsy from infants and children dying from acute infective illness or as a result of trauma. All observations were carried out upon transverse sections of paraffin-embedded muscle from deltoid, biceps brachii, rectus femoris and gastrocnemius; the results are analysed and are related to body height and growth. There is a steady increase in muscle fibre diameter and area with increasing body size for each muscle examined and we provide figures against which changes in abnormal muscle can be compared.

AB - The results are reported of measurements of muscle fibre size, area and diameter in specimens of limb muscle obtained at autopsy from infants and children dying from acute infective illness or as a result of trauma. All observations were carried out upon transverse sections of paraffin-embedded muscle from deltoid, biceps brachii, rectus femoris and gastrocnemius; the results are analysed and are related to body height and growth. There is a steady increase in muscle fibre diameter and area with increasing body size for each muscle examined and we provide figures against which changes in abnormal muscle can be compared.

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Muscle fibre size in normal infants, children and adolescents. An autopsy study

Abstract

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