Muscle fatigue induced by stimulation with and without doublets

B. Bigland-Ritchie, I. Zijdewind, Christine K Thomas

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Muscles are usually stimulated by shocks delivered at some constant rate. However, human thenar motor units generate optimum force per pulse when excited by impulse trains that begin with one or two short interpulse intervals ('doublets'), followed by longer intervals. Our aim was to determine whether the rate of force and force-time integral reduction during fatigue of thenar muscles is influenced by an initial doublet, and/or the number of pulses per train. We first matched thenar force-time integral using two different pulse patterns, one of which began with a doublet. Fatigue induced by trains that contained a doublet resulted in slower rates of force and force-time integral reduction and smaller increases in half-relaxation time than that evoked by bursts of 40-Hz stimulation. When the force was measured in each protocol after equal numbers of pulses had been delivered, the force loss was still significantly less for pulse trains containing a doublet. These results have useful implications when designing stimulation to strengthen weak muscles or to drive paralyzed muscles. (C) 2000 John Wiley and Sons, Inc.

Original languageEnglish
Pages (from-to)1348-1355
Number of pages8
JournalMuscle and Nerve
Volume23
Issue number9
DOIs
StatePublished - Sep 25 2000

Fingerprint

Muscle Fatigue
Muscles
Fatigue
Shock

Keywords

  • Constant-frequency stimulation
  • Force-time integral
  • Muscle force
  • Paralyzed muscles
  • Thenar muscles
  • Variable frequency stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Muscle fatigue induced by stimulation with and without doublets. / Bigland-Ritchie, B.; Zijdewind, I.; Thomas, Christine K.

In: Muscle and Nerve, Vol. 23, No. 9, 25.09.2000, p. 1348-1355.

Research output: Contribution to journalArticle

Bigland-Ritchie, B. ; Zijdewind, I. ; Thomas, Christine K. / Muscle fatigue induced by stimulation with and without doublets. In: Muscle and Nerve. 2000 ; Vol. 23, No. 9. pp. 1348-1355.
@article{56ac2b1d8c1042ee9b69cb7734c3fbf7,
title = "Muscle fatigue induced by stimulation with and without doublets",
abstract = "Muscles are usually stimulated by shocks delivered at some constant rate. However, human thenar motor units generate optimum force per pulse when excited by impulse trains that begin with one or two short interpulse intervals ('doublets'), followed by longer intervals. Our aim was to determine whether the rate of force and force-time integral reduction during fatigue of thenar muscles is influenced by an initial doublet, and/or the number of pulses per train. We first matched thenar force-time integral using two different pulse patterns, one of which began with a doublet. Fatigue induced by trains that contained a doublet resulted in slower rates of force and force-time integral reduction and smaller increases in half-relaxation time than that evoked by bursts of 40-Hz stimulation. When the force was measured in each protocol after equal numbers of pulses had been delivered, the force loss was still significantly less for pulse trains containing a doublet. These results have useful implications when designing stimulation to strengthen weak muscles or to drive paralyzed muscles. (C) 2000 John Wiley and Sons, Inc.",
keywords = "Constant-frequency stimulation, Force-time integral, Muscle force, Paralyzed muscles, Thenar muscles, Variable frequency stimulation",
author = "B. Bigland-Ritchie and I. Zijdewind and Thomas, {Christine K}",
year = "2000",
month = "9",
day = "25",
doi = "10.1002/1097-4598(200009)23:9<1348::AID-MUS5>3.0.CO;2-0",
language = "English",
volume = "23",
pages = "1348--1355",
journal = "Muscle and Nerve",
issn = "0148-639X",
publisher = "John Wiley and Sons Inc.",
number = "9",

}

TY - JOUR

T1 - Muscle fatigue induced by stimulation with and without doublets

AU - Bigland-Ritchie, B.

AU - Zijdewind, I.

AU - Thomas, Christine K

PY - 2000/9/25

Y1 - 2000/9/25

N2 - Muscles are usually stimulated by shocks delivered at some constant rate. However, human thenar motor units generate optimum force per pulse when excited by impulse trains that begin with one or two short interpulse intervals ('doublets'), followed by longer intervals. Our aim was to determine whether the rate of force and force-time integral reduction during fatigue of thenar muscles is influenced by an initial doublet, and/or the number of pulses per train. We first matched thenar force-time integral using two different pulse patterns, one of which began with a doublet. Fatigue induced by trains that contained a doublet resulted in slower rates of force and force-time integral reduction and smaller increases in half-relaxation time than that evoked by bursts of 40-Hz stimulation. When the force was measured in each protocol after equal numbers of pulses had been delivered, the force loss was still significantly less for pulse trains containing a doublet. These results have useful implications when designing stimulation to strengthen weak muscles or to drive paralyzed muscles. (C) 2000 John Wiley and Sons, Inc.

AB - Muscles are usually stimulated by shocks delivered at some constant rate. However, human thenar motor units generate optimum force per pulse when excited by impulse trains that begin with one or two short interpulse intervals ('doublets'), followed by longer intervals. Our aim was to determine whether the rate of force and force-time integral reduction during fatigue of thenar muscles is influenced by an initial doublet, and/or the number of pulses per train. We first matched thenar force-time integral using two different pulse patterns, one of which began with a doublet. Fatigue induced by trains that contained a doublet resulted in slower rates of force and force-time integral reduction and smaller increases in half-relaxation time than that evoked by bursts of 40-Hz stimulation. When the force was measured in each protocol after equal numbers of pulses had been delivered, the force loss was still significantly less for pulse trains containing a doublet. These results have useful implications when designing stimulation to strengthen weak muscles or to drive paralyzed muscles. (C) 2000 John Wiley and Sons, Inc.

KW - Constant-frequency stimulation

KW - Force-time integral

KW - Muscle force

KW - Paralyzed muscles

KW - Thenar muscles

KW - Variable frequency stimulation

UR - http://www.scopus.com/inward/record.url?scp=0033811937&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033811937&partnerID=8YFLogxK

U2 - 10.1002/1097-4598(200009)23:9<1348::AID-MUS5>3.0.CO;2-0

DO - 10.1002/1097-4598(200009)23:9<1348::AID-MUS5>3.0.CO;2-0

M3 - Article

C2 - 10951437

AN - SCOPUS:0033811937

VL - 23

SP - 1348

EP - 1355

JO - Muscle and Nerve

JF - Muscle and Nerve

SN - 0148-639X

IS - 9

ER -