Murine Models Demonstrate Distinct Vasculogenic and Cardiomyogenic cKit+ Lineages in the Heart

Konstantinos E. Hatzistergos, Joshua Hare

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

After 2 recent genetic studies in mice addressing the developmental origins1 and regenerative activity of cardiac cKit+ cells,2 2 additional reports by Sultana et al3 and Liu et al4 provide further information on the expression of cKit in the embryonic and adult hearts. Here, we synthesize the findings from the 4 distinct cKit models to gain insights into the biology of this important cell type.

Original languageEnglish (US)
Pages (from-to)382-387
Number of pages6
JournalCirculation Research
Volume118
Issue number3
DOIs
StatePublished - 2016

Keywords

  • Cardiac
  • Cell differentiation
  • Cell- and tissue-based therapy
  • Coronary vessels
  • Endothelial cells
  • Myocytes

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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