Multiple sclerosis and human T-cell lymphotropic retroviruses

Hilary Koprowski, Elaine C. Defreitas, Mary E. Harper, Magnhild Sandberg-Wollheim, William A. Sheremata, Marjorie Robert-Guroff, Carl W. Saxinger, Mark B. Feinberg, Flossie Wong-Staal, Robert C. Gallo

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285 Scopus citations

Abstract

A combination of different types of data suggests that some multiple sclerosis patients respond immunologically to, and have cerebrospinal T cells containing, a retrovirus that is related to, but distinct from, the three types of human T-cell lymphotropic viruses. The role of this virus in multiple sclerosis is uncertain.

Original languageEnglish (US)
Pages (from-to)154-160
Number of pages7
JournalNature
Volume318
Issue number6042
DOIs
StatePublished - 1985
Externally publishedYes

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    Koprowski, H., Defreitas, E. C., Harper, M. E., Sandberg-Wollheim, M., Sheremata, W. A., Robert-Guroff, M., Saxinger, C. W., Feinberg, M. B., Wong-Staal, F., & Gallo, R. C. (1985). Multiple sclerosis and human T-cell lymphotropic retroviruses. Nature, 318(6042), 154-160. https://doi.org/10.1038/318154a0