Multimodal imaging of sarcoid choroidal granulomas

Yasha S. Modi, Aliza Epstein, Swetangi Bhaleeya, J. William Harbour, Thomas A Albini

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Enhanced-depth imaging optical coherence tomography (EDI-OCT) provides high-resolution imaging of the choroid. Herein, we report multimodal imaging, including EDI-OCT, of a case of sarcoid choroidal granulomas. Findings: A 63-year-old female with biopsy-supported sarcoidosis presented with unilateral multifocal choroidal granulomas. Enhanced-depth imaging optical coherence tomography (EDI-OCT) demonstrated a homogenous hyporeflective choroidal lesion with choriocapillaris thinning and sparing of the surrounding choroid. The patient was started on oral steroids with a weekly taper schedule. Within 5 weeks, the choroidal lesions had clinically resolved with return of normal-appearing choroidal architecture on EDI-OCT. Indocyanine green angiography, however, demonstrated hypofluoresence at the sites of choroidal granulomas 11 months after the clinical resolution, suggesting a longstanding choroidal perfusion deficit undetected by OCT. Conclusions: Choroidal imaging via EDI-OCT provides detailed morphologic information of sarcoid granulomas and can accurately demonstrate structural resolution of the lesions.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalJournal of Ophthalmic Inflammation and Infection
Volume3
Issue number1
DOIs
StatePublished - Dec 1 2013

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Multimodal Imaging
Optical Coherence Tomography
Granuloma
Choroid
Indocyanine Green
Sarcoidosis
Appointments and Schedules
Angiography
Perfusion
Steroids
Biopsy

Keywords

  • Choroidal granuloma
  • Enhanced-depth imaging optical coherence tomography
  • Imaging
  • Indocyanine green
  • Sarcoidosis

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases

Cite this

Multimodal imaging of sarcoid choroidal granulomas. / Modi, Yasha S.; Epstein, Aliza; Bhaleeya, Swetangi; William Harbour, J.; Albini, Thomas A.

In: Journal of Ophthalmic Inflammation and Infection, Vol. 3, No. 1, 01.12.2013, p. 1-4.

Research output: Contribution to journalArticle

Modi, Yasha S. ; Epstein, Aliza ; Bhaleeya, Swetangi ; William Harbour, J. ; Albini, Thomas A. / Multimodal imaging of sarcoid choroidal granulomas. In: Journal of Ophthalmic Inflammation and Infection. 2013 ; Vol. 3, No. 1. pp. 1-4.
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