Multimodal imaging of sarcoid choroidal granulomas

Yasha S. Modi, Aliza Epstein, Swetangi Bhaleeya, J. William Harbour, Thomas Albini

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Background: Enhanced-depth imaging optical coherence tomography (EDI-OCT) provides high-resolution imaging of the choroid. Herein, we report multimodal imaging, including EDI-OCT, of a case of sarcoid choroidal granulomas. Findings: A 63-year-old female with biopsy-supported sarcoidosis presented with unilateral multifocal choroidal granulomas. Enhanced-depth imaging optical coherence tomography (EDI-OCT) demonstrated a homogenous hyporeflective choroidal lesion with choriocapillaris thinning and sparing of the surrounding choroid. The patient was started on oral steroids with a weekly taper schedule. Within 5 weeks, the choroidal lesions had clinically resolved with return of normal-appearing choroidal architecture on EDI-OCT. Indocyanine green angiography, however, demonstrated hypofluoresence at the sites of choroidal granulomas 11 months after the clinical resolution, suggesting a longstanding choroidal perfusion deficit undetected by OCT. Conclusions: Choroidal imaging via EDI-OCT provides detailed morphologic information of sarcoid granulomas and can accurately demonstrate structural resolution of the lesions.

Original languageEnglish (US)
Article number58
Pages (from-to)1-4
Number of pages4
JournalJournal of Ophthalmic Inflammation and Infection
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2013

Keywords

  • Choroidal granuloma
  • Enhanced-depth imaging optical coherence tomography
  • Imaging
  • Indocyanine green
  • Sarcoidosis

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases

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