Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru

Pablo E. Campos, Pedro G. Suarez, Jorge Sanchez, David Zavala, Jorge Arevalo, Eduardo Ticona, Charles M. Nolan, Thomas Hooton, King K. Holmes

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

During 1999 to 2000, we identified HIV-infected persons with new episodes of tuberculosis (TB) at 10 hospitals in Lima, Peru, and a random sample of other Lima residents with TB. Multidrug-resistant (MDR)-TB was documented in 35 (43%) of 81 HIV-positive patients and 38 (3.9%) of 965 patients who were HIV-negative or of unknown HIV status (p < 0.001). HIV-positive patients with MDR-TB were concentrated at three hospitals that treat the greatest numbers of HIV-infected persons with TB. Of patients with TB, those with HIV infection differed from those without known HIV infection in having more frequent prior exposure to clinical services and more frequent previous TB therapy or prophylaxis. However, MDR-TB in HIV-infected patients was not associated with previous TB therapy or prophylaxis. MDR-TB is an ongoing problem in HIV-infected persons receiving care in public hospitals in Lima and Callao; they represent sentinel cases for a potentially larger epidemic of nosocomial MDR-TB.

Original languageEnglish
Pages (from-to)1571-1578
Number of pages8
JournalEmerging Infectious Diseases
Volume9
Issue number12
StatePublished - Dec 1 2003
Externally publishedYes

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Multidrug-Resistant Tuberculosis
Peru
Mycobacterium tuberculosis
HIV
Tuberculosis
HIV Infections
Public Hospitals
Therapeutics

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Campos, P. E., Suarez, P. G., Sanchez, J., Zavala, D., Arevalo, J., Ticona, E., ... Holmes, K. K. (2003). Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru. Emerging Infectious Diseases, 9(12), 1571-1578.

Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru. / Campos, Pablo E.; Suarez, Pedro G.; Sanchez, Jorge; Zavala, David; Arevalo, Jorge; Ticona, Eduardo; Nolan, Charles M.; Hooton, Thomas; Holmes, King K.

In: Emerging Infectious Diseases, Vol. 9, No. 12, 01.12.2003, p. 1571-1578.

Research output: Contribution to journalArticle

Campos, PE, Suarez, PG, Sanchez, J, Zavala, D, Arevalo, J, Ticona, E, Nolan, CM, Hooton, T & Holmes, KK 2003, 'Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru', Emerging Infectious Diseases, vol. 9, no. 12, pp. 1571-1578.
Campos PE, Suarez PG, Sanchez J, Zavala D, Arevalo J, Ticona E et al. Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru. Emerging Infectious Diseases. 2003 Dec 1;9(12):1571-1578.
Campos, Pablo E. ; Suarez, Pedro G. ; Sanchez, Jorge ; Zavala, David ; Arevalo, Jorge ; Ticona, Eduardo ; Nolan, Charles M. ; Hooton, Thomas ; Holmes, King K. / Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru. In: Emerging Infectious Diseases. 2003 ; Vol. 9, No. 12. pp. 1571-1578.
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