Multi-sectional views textural based SVM for MS lesion segmentation in multi-channels MRIs

Bassem A. Abdullah, Akmal A. Younis, Nigel M. John

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

In this paper, a new technique is proposed for automatic segmentation of multiple sclerosis (MS) lesions from brain magnetic resonance imaging (MRI) data. The technique uses a trained support vector machine (SVM) to discriminate between the blocks in regions of MS lesions and the blocks in non-MS lesion regions mainly based on the textural features with aid of the other features. The classification is done on each of the axial, sagittal and coronal sectional brain view independently and the resultant segmentations are aggregated to provide more accurate output segmentation. The main contribution of the proposed technique described in this paper is the use of textural features to detect MS lesions in a fully automated approach that does not rely on manually delineating the MS lesions. In addition, the technique introduces the concept of the multi-sectional view segmentation to produce verified segmentation. The proposed textural-based SVM technique was evaluated using three simulated datasets and more than fifty real MRI datasets. The results were compared with state of the art methods. The obtained results indicate that the proposed method would be viable for use in clinical practice for the detection of MS lesions in MRI.

Original languageEnglish (US)
Pages (from-to)56-72
Number of pages17
JournalOpen Biomedical Engineering Journal
Volume6
Issue number1
DOIs
StatePublished - 2012

Keywords

  • Brain segmentation
  • MRI
  • Multi-channels
  • Multiple sclerosis
  • ROI
  • Sectional view
  • SVM
  • Texture analysis

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering

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