Multi-drug resistant Mycobacterium chelonae scleral buckle infection

Daniel S. Churgin, Kimberly D. Tran, Ninel Gregori, Ryan C. Young, Chrisfouad Raif Alabiad, Harry W Flynn

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: To describe a case of Multi-drug resistant Mycobacterium chelonae scleral buckle infection. Observations: A 56 year-old male with history of retinal detachment repair with scleral buckle 20 years prior presented with 8 months of intermittent pain and redness in the left eye. The patient was diagnosed with scleral buckle infection, the buckle was removed, and cultures revealed multi-drug resistant Mycobacterium chelonae. The postoperative course included orbital cellulitis treated with systemic linezolid, clarithromycin, and imipenem. All systemic antibiotics were discontinued on post-operative day 25, visual acuity improved to 20/25, the retina remained attached, and no recurrence occurred over 3 years of follow-up. Conclusions and importance: NTM infections are typically chronic and often require lengthy treatment. SB infection is rare, but often associated with biofilm and antibiotic resistance. In spite of removing the SB, anchoring sutures, sheath surrounding the buckle and associated biofilm, a prolonged course of systemic antibiotics may be necessary in some patients.

Original languageEnglish (US)
Pages (from-to)276-278
Number of pages3
JournalAmerican Journal of Ophthalmology Case Reports
Volume10
DOIs
StatePublished - Jun 1 2018

Fingerprint

Mycobacterium chelonae
Linezolid
Biofilms
Infection
Pharmaceutical Preparations
Orbital Cellulitis
Anti-Bacterial Agents
Clarithromycin
Imipenem
Retinal Detachment
Microbial Drug Resistance
Sutures
Visual Acuity
Retina
Recurrence
Pain

Keywords

  • Non-tuberculous mycobacterium
  • Orbital cellulitis
  • Scleral buckle

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Multi-drug resistant Mycobacterium chelonae scleral buckle infection. / Churgin, Daniel S.; Tran, Kimberly D.; Gregori, Ninel; Young, Ryan C.; Alabiad, Chrisfouad Raif; Flynn, Harry W.

In: American Journal of Ophthalmology Case Reports, Vol. 10, 01.06.2018, p. 276-278.

Research output: Contribution to journalArticle

@article{519c5f90e2414fbe92668f5b04d09116,
title = "Multi-drug resistant Mycobacterium chelonae scleral buckle infection",
abstract = "Purpose: To describe a case of Multi-drug resistant Mycobacterium chelonae scleral buckle infection. Observations: A 56 year-old male with history of retinal detachment repair with scleral buckle 20 years prior presented with 8 months of intermittent pain and redness in the left eye. The patient was diagnosed with scleral buckle infection, the buckle was removed, and cultures revealed multi-drug resistant Mycobacterium chelonae. The postoperative course included orbital cellulitis treated with systemic linezolid, clarithromycin, and imipenem. All systemic antibiotics were discontinued on post-operative day 25, visual acuity improved to 20/25, the retina remained attached, and no recurrence occurred over 3 years of follow-up. Conclusions and importance: NTM infections are typically chronic and often require lengthy treatment. SB infection is rare, but often associated with biofilm and antibiotic resistance. In spite of removing the SB, anchoring sutures, sheath surrounding the buckle and associated biofilm, a prolonged course of systemic antibiotics may be necessary in some patients.",
keywords = "Non-tuberculous mycobacterium, Orbital cellulitis, Scleral buckle",
author = "Churgin, {Daniel S.} and Tran, {Kimberly D.} and Ninel Gregori and Young, {Ryan C.} and Alabiad, {Chrisfouad Raif} and Flynn, {Harry W}",
year = "2018",
month = "6",
day = "1",
doi = "10.1016/j.ajoc.2018.04.004",
language = "English (US)",
volume = "10",
pages = "276--278",
journal = "American Journal of Ophthalmology Case Reports",
issn = "2451-9936",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Multi-drug resistant Mycobacterium chelonae scleral buckle infection

AU - Churgin, Daniel S.

AU - Tran, Kimberly D.

AU - Gregori, Ninel

AU - Young, Ryan C.

AU - Alabiad, Chrisfouad Raif

AU - Flynn, Harry W

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Purpose: To describe a case of Multi-drug resistant Mycobacterium chelonae scleral buckle infection. Observations: A 56 year-old male with history of retinal detachment repair with scleral buckle 20 years prior presented with 8 months of intermittent pain and redness in the left eye. The patient was diagnosed with scleral buckle infection, the buckle was removed, and cultures revealed multi-drug resistant Mycobacterium chelonae. The postoperative course included orbital cellulitis treated with systemic linezolid, clarithromycin, and imipenem. All systemic antibiotics were discontinued on post-operative day 25, visual acuity improved to 20/25, the retina remained attached, and no recurrence occurred over 3 years of follow-up. Conclusions and importance: NTM infections are typically chronic and often require lengthy treatment. SB infection is rare, but often associated with biofilm and antibiotic resistance. In spite of removing the SB, anchoring sutures, sheath surrounding the buckle and associated biofilm, a prolonged course of systemic antibiotics may be necessary in some patients.

AB - Purpose: To describe a case of Multi-drug resistant Mycobacterium chelonae scleral buckle infection. Observations: A 56 year-old male with history of retinal detachment repair with scleral buckle 20 years prior presented with 8 months of intermittent pain and redness in the left eye. The patient was diagnosed with scleral buckle infection, the buckle was removed, and cultures revealed multi-drug resistant Mycobacterium chelonae. The postoperative course included orbital cellulitis treated with systemic linezolid, clarithromycin, and imipenem. All systemic antibiotics were discontinued on post-operative day 25, visual acuity improved to 20/25, the retina remained attached, and no recurrence occurred over 3 years of follow-up. Conclusions and importance: NTM infections are typically chronic and often require lengthy treatment. SB infection is rare, but often associated with biofilm and antibiotic resistance. In spite of removing the SB, anchoring sutures, sheath surrounding the buckle and associated biofilm, a prolonged course of systemic antibiotics may be necessary in some patients.

KW - Non-tuberculous mycobacterium

KW - Orbital cellulitis

KW - Scleral buckle

UR - http://www.scopus.com/inward/record.url?scp=85045035356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045035356&partnerID=8YFLogxK

U2 - 10.1016/j.ajoc.2018.04.004

DO - 10.1016/j.ajoc.2018.04.004

M3 - Article

AN - SCOPUS:85045035356

VL - 10

SP - 276

EP - 278

JO - American Journal of Ophthalmology Case Reports

JF - American Journal of Ophthalmology Case Reports

SN - 2451-9936

ER -