Multi-channel recordings of the motor activity from the spinal cord of behaving rats

Abhishek Prasad, Mesut Sahin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The objective of this study was to extract voluntary motor signals from the rubrospinal tract in behaving rats and study the correlation between these volitional signals and the elbow movements. Multi-contact silicone substrate surface electrodes were implanted chronically at the cervical C5-C6 and C6-C7 levels of the spinal cord. Recordings were made during face cleaning by the animal as this task involves cyclic movements of the forelimbs and does not require any training. Temporal correlation was performed between the recordings of the proximal pair and the distal pair of contacts within a sliding window to determine whether the signals were sensory or motor. Linear regression technique was used to reconstruct the arm movement from the rectified-integrated version of the neural signals. The preliminary data show that motor signals can be successfully recorded from the cervical region of the spinal cord in behaving rats and reconstruction of elbow movements from the neural signals is feasible using these non-penetrating surface electrodes.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2288-2291
Number of pages4
DOIs
StatePublished - 2006
Externally publishedYes
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

Fingerprint

Rats
Electrodes
Silicones
Linear regression
Cleaning
Animals
Substrates

Keywords

  • Brain-computer interface (BCI)
  • Lateral corticospinal tract (LCST)
  • Rubrospinal tract (RST)
  • Spinal cord injury (SCI)

ASJC Scopus subject areas

  • Bioengineering

Cite this

Prasad, A., & Sahin, M. (2006). Multi-channel recordings of the motor activity from the spinal cord of behaving rats. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 2288-2291). [4030456] https://doi.org/10.1109/IEMBS.2006.260854

Multi-channel recordings of the motor activity from the spinal cord of behaving rats. / Prasad, Abhishek; Sahin, Mesut.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 2288-2291 4030456.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Prasad, A & Sahin, M 2006, Multi-channel recordings of the motor activity from the spinal cord of behaving rats. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4030456, pp. 2288-2291, 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06, New York, NY, United States, 8/30/06. https://doi.org/10.1109/IEMBS.2006.260854
Prasad A, Sahin M. Multi-channel recordings of the motor activity from the spinal cord of behaving rats. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 2288-2291. 4030456 https://doi.org/10.1109/IEMBS.2006.260854
Prasad, Abhishek ; Sahin, Mesut. / Multi-channel recordings of the motor activity from the spinal cord of behaving rats. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. pp. 2288-2291
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