Multi-channel recordings of the motor activity from the spinal cord of behaving rats

Abhishek Prasad, Mesut Sahin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

The objective of this study was to extract voluntary motor signals from the rubrospinal tract in behaving rats and study the correlation between these volitional signals and the elbow movements. Multi-contact silicone substrate surface electrodes were implanted chronically at the cervical C5-C6 and C6-C7 levels of the spinal cord. Recordings were made during face cleaning by the animal as this task involves cyclic movements of the forelimbs and does not require any training. Temporal correlation was performed between the recordings of the proximal pair and the distal pair of contacts within a sliding window to determine whether the signals were sensory or motor. Linear regression technique was used to reconstruct the arm movement from the rectified-integrated version of the neural signals. The preliminary data show that motor signals can be successfully recorded from the cervical region of the spinal cord in behaving rats and reconstruction of elbow movements from the neural signals is feasible using these non-penetrating surface electrodes.

Original languageEnglish (US)
Title of host publication28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Pages2288-2291
Number of pages4
DOIs
StatePublished - 2006
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

Keywords

  • Brain-computer interface (BCI)
  • Lateral corticospinal tract (LCST)
  • Rubrospinal tract (RST)
  • Spinal cord injury (SCI)

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • Cite this

    Prasad, A., & Sahin, M. (2006). Multi-channel recordings of the motor activity from the spinal cord of behaving rats. In 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 (pp. 2288-2291). [4030456] (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). https://doi.org/10.1109/IEMBS.2006.260854