Abstract
Purpose: To report the clinicopathologic features of a patient with mucosa-associated lymphoid tissue (MALT) lymphoma of the conjunctiva and associated intraocular involvement. Methods: This study is a retrospective clinicopathologic correlative case report summarizing the clinical, radiologic, and histopathologic findings of a patient with conjunctival MALT lymphoma and associated intraocular involvement. Results: Ophthalmic examination and fluorescein angiography demonstrated progressive conjunctival infiltration bilaterally, marked uveal effusions in the left eye, and cellular white infiltrates of the choroid in the right eye. MRI of the orbit revealed a diffusely infiltrating intra- and extraocular lesion extending around the globe and optic nerve in the left eye without evidence of intracranial extension. Conjunctival biopsy showed low-grade tumor cells, consistent with the diagnosis of MALT lymphoma. The patient was successfully treated with external beam radiation with marked clinical improvement. Conclusion: Conjunctival MALT lymphomas, typically indolent and localized tumors, may extend into the orbit and invade local tissues such as the choroid with devastating consequences. A conjunctival biopsy can provide an easy diagnosis of this treatable entity.
| Original language | English |
|---|---|
| Pages (from-to) | 94-98 |
| Number of pages | 5 |
| Journal | Retina |
| Volume | 25 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2005 |
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Keywords
- Choroidal infiltrates
- Conjunctival MALT lymphoma
- Intraocular neoplasm
- MALT lymphoma
- Mucosa-associated lymphoid tissue lymphoma
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
Cite this
Mucosa-associated lymphoid tissue lymphoma with intraocular involvement. / Sarraf, David; Jain, Atul; Dubovy, Sander; Kreiger, Allan; Fong, Donald; Paschal, John.
In: Retina, Vol. 25, No. 1, 01.01.2005, p. 94-98.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mucosa-associated lymphoid tissue lymphoma with intraocular involvement
AU - Sarraf, David
AU - Jain, Atul
AU - Dubovy, Sander
AU - Kreiger, Allan
AU - Fong, Donald
AU - Paschal, John
PY - 2005/1/1
Y1 - 2005/1/1
N2 - Purpose: To report the clinicopathologic features of a patient with mucosa-associated lymphoid tissue (MALT) lymphoma of the conjunctiva and associated intraocular involvement. Methods: This study is a retrospective clinicopathologic correlative case report summarizing the clinical, radiologic, and histopathologic findings of a patient with conjunctival MALT lymphoma and associated intraocular involvement. Results: Ophthalmic examination and fluorescein angiography demonstrated progressive conjunctival infiltration bilaterally, marked uveal effusions in the left eye, and cellular white infiltrates of the choroid in the right eye. MRI of the orbit revealed a diffusely infiltrating intra- and extraocular lesion extending around the globe and optic nerve in the left eye without evidence of intracranial extension. Conjunctival biopsy showed low-grade tumor cells, consistent with the diagnosis of MALT lymphoma. The patient was successfully treated with external beam radiation with marked clinical improvement. Conclusion: Conjunctival MALT lymphomas, typically indolent and localized tumors, may extend into the orbit and invade local tissues such as the choroid with devastating consequences. A conjunctival biopsy can provide an easy diagnosis of this treatable entity.
AB - Purpose: To report the clinicopathologic features of a patient with mucosa-associated lymphoid tissue (MALT) lymphoma of the conjunctiva and associated intraocular involvement. Methods: This study is a retrospective clinicopathologic correlative case report summarizing the clinical, radiologic, and histopathologic findings of a patient with conjunctival MALT lymphoma and associated intraocular involvement. Results: Ophthalmic examination and fluorescein angiography demonstrated progressive conjunctival infiltration bilaterally, marked uveal effusions in the left eye, and cellular white infiltrates of the choroid in the right eye. MRI of the orbit revealed a diffusely infiltrating intra- and extraocular lesion extending around the globe and optic nerve in the left eye without evidence of intracranial extension. Conjunctival biopsy showed low-grade tumor cells, consistent with the diagnosis of MALT lymphoma. The patient was successfully treated with external beam radiation with marked clinical improvement. Conclusion: Conjunctival MALT lymphomas, typically indolent and localized tumors, may extend into the orbit and invade local tissues such as the choroid with devastating consequences. A conjunctival biopsy can provide an easy diagnosis of this treatable entity.
KW - Choroidal infiltrates
KW - Conjunctival MALT lymphoma
KW - Intraocular neoplasm
KW - MALT lymphoma
KW - Mucosa-associated lymphoid tissue lymphoma
UR - http://www.scopus.com/inward/record.url?scp=13844265718&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=13844265718&partnerID=8YFLogxK
U2 - 10.1097/00006982-200501000-00018
DO - 10.1097/00006982-200501000-00018
M3 - Article
C2 - 15655452
AN - SCOPUS:13844265718
VL - 25
SP - 94
EP - 98
JO - Retina
JF - Retina
SN - 0275-004X
IS - 1
ER -