MSH activity in pituitaries of rats treated with hypothalamic extracts from various animals

Abba J. Kastin, Andrew V. Schally

Research output: Contribution to journalArticle

24 Scopus citations


Hypothalamic extracts from frog, rabbit, kitten, sheep, pig, and man were found to increase the melanocyte-stimulating hormone (MSH) content of rat pituitary glands. Frog hypothalamic extracts also lightened frogs previously darkened by removal of the hypothalamic region. The results indicate the presence of MSH-release inhibiting factor (MIF) in the hypothalami of frogs and several mammals.

Original languageEnglish (US)
Pages (from-to)344-347
Number of pages4
JournalGeneral and Comparative Endocrinology
Issue number2
StatePublished - Apr 1967


ASJC Scopus subject areas

  • Animal Science and Zoology
  • Endocrinology

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