MSCs for diabetes

Luca A Inverardi; Giacomo Lanzoni; Juan Dominguez-Bendala; Camillo Ricordi

doi:10.1007/978-1-4614-5711-4_33

MSCs for diabetes

Luca A Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala, Camillo Ricordi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

Original language	English (US)
Title of host publication	Mesenchymal Stromal Cells
Subtitle of host publication	Biology and Clinical Applications
Publisher	Springer New York
Pages	571-597
Number of pages	27
ISBN (Electronic)	9781461457114
ISBN (Print)	9781461457107
DOIs	https://doi.org/10.1007/978-1-4614-5711-4_33
State	Published - Jan 1 2013

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1007/978-1-4614-5711-4_33

Fingerprint Dive into the research topics of 'MSCs for diabetes'. Together they form a unique fingerprint.

Cite this

@inbook{a03c055d44be4a43b7a35ba30f4ab72b,

title = "MSCs for diabetes",

abstract = "Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.",

author = "Inverardi, {Luca A} and Giacomo Lanzoni and Juan Dominguez-Bendala and Camillo Ricordi",

year = "2013",

month = jan,

day = "1",

doi = "10.1007/978-1-4614-5711-4_33",

language = "English (US)",

isbn = "9781461457107",

pages = "571--597",

booktitle = "Mesenchymal Stromal Cells",

publisher = "Springer New York",

}

TY - CHAP

T1 - MSCs for diabetes

AU - Inverardi, Luca A

AU - Lanzoni, Giacomo

AU - Dominguez-Bendala, Juan

AU - Ricordi, Camillo

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

AB - Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

UR - http://www.scopus.com/inward/record.url?scp=85021671546&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021671546&partnerID=8YFLogxK

U2 - 10.1007/978-1-4614-5711-4_33

DO - 10.1007/978-1-4614-5711-4_33

M3 - Chapter

AN - SCOPUS:85021671546

SN - 9781461457107

SP - 571

EP - 597

BT - Mesenchymal Stromal Cells

PB - Springer New York

ER -