MSCs for diabetes

Luca A Inverardi; Giacomo Lanzoni; Juan Dominguez-Bendala; Camillo Ricordi

doi:10.1007/978-1-4614-5711-4_33

MSCs for diabetes

Luca A Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala, Camillo Ricordi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

Original language	English (US)
Title of host publication	Mesenchymal Stromal Cells
Subtitle of host publication	Biology and Clinical Applications
Publisher	Springer New York
Pages	571-597
Number of pages	27
ISBN (Electronic)	9781461457114
ISBN (Print)	9781461457107
DOIs	https://doi.org/10.1007/978-1-4614-5711-4_33
State	Published - Jan 1 2013

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-1-4614-5711-4_33

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title = "MSCs for diabetes",

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AU - Inverardi, Luca A

AU - Lanzoni, Giacomo

AU - Dominguez-Bendala, Juan

AU - Ricordi, Camillo

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AB - Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

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MSCs for diabetes

Abstract

ASJC Scopus subject areas

UN SDGs

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