MSCs for diabetes

Luca A Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala, Camillo Ricordi

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

Original languageEnglish (US)
Title of host publicationMesenchymal Stromal Cells
Subtitle of host publicationBiology and Clinical Applications
PublisherSpringer New York
Pages571-597
Number of pages27
ISBN (Electronic)9781461457114
ISBN (Print)9781461457107
DOIs
StatePublished - Jan 1 2013

Fingerprint

Medical problems
Stem cells
Mesenchymal Stromal Cells
Type 1 Diabetes Mellitus
Mesoderm
Autoimmunity
Plasticity
Cell Differentiation
Inflammation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Inverardi, L. A., Lanzoni, G., Dominguez-Bendala, J., & Ricordi, C. (2013). MSCs for diabetes. In Mesenchymal Stromal Cells: Biology and Clinical Applications (pp. 571-597). Springer New York. https://doi.org/10.1007/978-1-4614-5711-4_33

MSCs for diabetes. / Inverardi, Luca A; Lanzoni, Giacomo; Dominguez-Bendala, Juan; Ricordi, Camillo.

Mesenchymal Stromal Cells: Biology and Clinical Applications. Springer New York, 2013. p. 571-597.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inverardi, LA, Lanzoni, G, Dominguez-Bendala, J & Ricordi, C 2013, MSCs for diabetes. in Mesenchymal Stromal Cells: Biology and Clinical Applications. Springer New York, pp. 571-597. https://doi.org/10.1007/978-1-4614-5711-4_33
Inverardi LA, Lanzoni G, Dominguez-Bendala J, Ricordi C. MSCs for diabetes. In Mesenchymal Stromal Cells: Biology and Clinical Applications. Springer New York. 2013. p. 571-597 https://doi.org/10.1007/978-1-4614-5711-4_33
Inverardi, Luca A ; Lanzoni, Giacomo ; Dominguez-Bendala, Juan ; Ricordi, Camillo. / MSCs for diabetes. Mesenchymal Stromal Cells: Biology and Clinical Applications. Springer New York, 2013. pp. 571-597
@inbook{a03c055d44be4a43b7a35ba30f4ab72b,
title = "MSCs for diabetes",
abstract = "Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.",
author = "Inverardi, {Luca A} and Giacomo Lanzoni and Juan Dominguez-Bendala and Camillo Ricordi",
year = "2013",
month = "1",
day = "1",
doi = "10.1007/978-1-4614-5711-4_33",
language = "English (US)",
isbn = "9781461457107",
pages = "571--597",
booktitle = "Mesenchymal Stromal Cells",
publisher = "Springer New York",

}

TY - CHAP

T1 - MSCs for diabetes

AU - Inverardi, Luca A

AU - Lanzoni, Giacomo

AU - Dominguez-Bendala, Juan

AU - Ricordi, Camillo

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

AB - Mesenchymal stromal cells (also often referred to as mesenchymal stem cells, MSCs) hold promise as a powerful tool in the treatment of human diseases. Because of their potent immunomodulatory properties, they are likely to impact in a positive fashion diseases in which inflammation and/or autoimmunity play a key role. Furthermore, they have been shown to possess plasticity as precursors of cells of various types. Their differentiation potential could span cell differentiation products that do not normally derive from the mesoderm, including cells of endodermal origin. These two remarkable features make them potentially ideal candidates for regenerative approaches. This chapter will briefly discuss the current state of the art in the emerging field of their use for autoimmune type 1 diabetes.

UR - http://www.scopus.com/inward/record.url?scp=85021671546&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021671546&partnerID=8YFLogxK

U2 - 10.1007/978-1-4614-5711-4_33

DO - 10.1007/978-1-4614-5711-4_33

M3 - Chapter

SN - 9781461457107

SP - 571

EP - 597

BT - Mesenchymal Stromal Cells

PB - Springer New York

ER -