Abstract
The preoperative assessment and surgical management of children and young adults with MRI-negative, frontal lobe epilepsy is often challenging owing to the semiologic expression being unusual or non-lateralizing. Localization based on functional tests may be non-convergent, further compounding the difficulty of surgical planning. We describe a patient with seizures presenting with early, subjective akinesia of the dominant hand that were at times triggered by repetitive motor tasks. Subdural EEG monitoring revealed seizure-origin in the ipsilateral dorsolateral frontal lobe. After resective surgery the patient has had a seizure free period of 9 months, and is free of deficits. This is the first report of frontal lobe seizure semiology consisting of ipsilateral ictal akinesia.
| Original language | English |
|---|---|
| Pages (from-to) | 349-355 |
| Number of pages | 7 |
| Journal | Epileptic Disorders |
| Volume | 10 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1 2008 |
Fingerprint
Keywords
- Childhood epilepsy
- Epilepsy surgery
- Frontal lobe epilepsy
- Presurgical assessment
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation. / Malone, Stephen; Miller, Ian; Jakayar, Prasanna; Resnick, Trevor; Bhatia, Sanjiv; Duchowny, Michael.
In: Epileptic Disorders, Vol. 10, No. 4, 01.12.2008, p. 349-355.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation
AU - Malone, Stephen
AU - Miller, Ian
AU - Jakayar, Prasanna
AU - Resnick, Trevor
AU - Bhatia, Sanjiv
AU - Duchowny, Michael
PY - 2008/12/1
Y1 - 2008/12/1
N2 - The preoperative assessment and surgical management of children and young adults with MRI-negative, frontal lobe epilepsy is often challenging owing to the semiologic expression being unusual or non-lateralizing. Localization based on functional tests may be non-convergent, further compounding the difficulty of surgical planning. We describe a patient with seizures presenting with early, subjective akinesia of the dominant hand that were at times triggered by repetitive motor tasks. Subdural EEG monitoring revealed seizure-origin in the ipsilateral dorsolateral frontal lobe. After resective surgery the patient has had a seizure free period of 9 months, and is free of deficits. This is the first report of frontal lobe seizure semiology consisting of ipsilateral ictal akinesia.
AB - The preoperative assessment and surgical management of children and young adults with MRI-negative, frontal lobe epilepsy is often challenging owing to the semiologic expression being unusual or non-lateralizing. Localization based on functional tests may be non-convergent, further compounding the difficulty of surgical planning. We describe a patient with seizures presenting with early, subjective akinesia of the dominant hand that were at times triggered by repetitive motor tasks. Subdural EEG monitoring revealed seizure-origin in the ipsilateral dorsolateral frontal lobe. After resective surgery the patient has had a seizure free period of 9 months, and is free of deficits. This is the first report of frontal lobe seizure semiology consisting of ipsilateral ictal akinesia.
KW - Childhood epilepsy
KW - Epilepsy surgery
KW - Frontal lobe epilepsy
KW - Presurgical assessment
UR - http://www.scopus.com/inward/record.url?scp=57049176080&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=57049176080&partnerID=8YFLogxK
U2 - 10.1684/epd.2008.0224
DO - 10.1684/epd.2008.0224
M3 - Article
VL - 10
SP - 349
EP - 355
JO - Epileptic Disorders
JF - Epileptic Disorders
SN - 1294-9361
IS - 4
ER -