MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation

Stephen Malone, Ian Miller, Prasanna Jakayar, Trevor Resnick, Sanjiv Bhatia, Michael Duchowny

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The preoperative assessment and surgical management of children and young adults with MRI-negative, frontal lobe epilepsy is often challenging owing to the semiologic expression being unusual or non-lateralizing. Localization based on functional tests may be non-convergent, further compounding the difficulty of surgical planning. We describe a patient with seizures presenting with early, subjective akinesia of the dominant hand that were at times triggered by repetitive motor tasks. Subdural EEG monitoring revealed seizure-origin in the ipsilateral dorsolateral frontal lobe. After resective surgery the patient has had a seizure free period of 9 months, and is free of deficits. This is the first report of frontal lobe seizure semiology consisting of ipsilateral ictal akinesia.

Original languageEnglish
Pages (from-to)349-355
Number of pages7
JournalEpileptic Disorders
Volume10
Issue number4
DOIs
StatePublished - Dec 1 2008

Fingerprint

Frontal Lobe Epilepsy
Reflex
Seizures
Frontal Lobe
Young Adult
Electroencephalography
Hand
Stroke

Keywords

  • Childhood epilepsy
  • Epilepsy surgery
  • Frontal lobe epilepsy
  • Presurgical assessment

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Malone, S., Miller, I., Jakayar, P., Resnick, T., Bhatia, S., & Duchowny, M. (2008). MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation. Epileptic Disorders, 10(4), 349-355. https://doi.org/10.1684/epd.2008.0224

MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation. / Malone, Stephen; Miller, Ian; Jakayar, Prasanna; Resnick, Trevor; Bhatia, Sanjiv; Duchowny, Michael.

In: Epileptic Disorders, Vol. 10, No. 4, 01.12.2008, p. 349-355.

Research output: Contribution to journalArticle

Malone, S, Miller, I, Jakayar, P, Resnick, T, Bhatia, S & Duchowny, M 2008, 'MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation', Epileptic Disorders, vol. 10, no. 4, pp. 349-355. https://doi.org/10.1684/epd.2008.0224
Malone S, Miller I, Jakayar P, Resnick T, Bhatia S, Duchowny M. MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation. Epileptic Disorders. 2008 Dec 1;10(4):349-355. https://doi.org/10.1684/epd.2008.0224
Malone, Stephen ; Miller, Ian ; Jakayar, Prasanna ; Resnick, Trevor ; Bhatia, Sanjiv ; Duchowny, Michael. / MRI-negative frontal lobe epilepsy with ipsilateral akinesia and reflex activation. In: Epileptic Disorders. 2008 ; Vol. 10, No. 4. pp. 349-355.
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