MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases

Noam Alperin, Y. Kadkhodayan, B. Varadarajalu, C. Fisher, B. Roitberg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The volumes of the intracranial space and the craniospinal system as a whole change during the cardiac cycle. These volume changes are caused by the pulsatile arterial inflow to the cranium, venous outflow from the cranium, and cerebrospinal fluid (CSF) flow that oscillates back and forth between the cranium and the spinal canal. The volume changes can be measured accurately and reproducibly using a dynamic, motion-sensitive MRI technique [1]. It appears intuitive that the volume change of the entire craniospinal system (CSVC) should be greater than the intracranial volume change (ICVC). However, since they exhibit varying temporal information, CSVC can be smaller than ICVC. In the present study, these volume changes were measured in healthy humans and trauma cases. In the trauma cases, it was found that CSVC was smaller than ICVC. The cause was found to be increased pulsatility in the venous flow channels. It is suspected that the resulting relationship between ICVC and CSVC is related to the incidence of trauma, and perhaps CSVC being smaller than ICVC could serve as an indicator.

Original languageEnglish (US)
Title of host publicationAnnual Reports of the Research Reactor Institute, Kyoto University
Pages270-273
Number of pages4
Volume1
StatePublished - 2001
Externally publishedYes
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: Oct 25 2001Oct 28 2001

Other

Other23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryTurkey
CityIstanbul
Period10/25/0110/28/01

Fingerprint

Cerebrospinal fluid
Canals
Channel flow
Magnetic resonance imaging
Flow of fluids

Keywords

  • Arterial flow
  • Craniospinal system
  • Craniospinal volume change
  • CSF flow
  • Head trauma
  • Intracranial volume change
  • Modulation transfer function
  • Venous flow

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Mechanical Engineering

Cite this

Alperin, N., Kadkhodayan, Y., Varadarajalu, B., Fisher, C., & Roitberg, B. (2001). MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases. In Annual Reports of the Research Reactor Institute, Kyoto University (Vol. 1, pp. 270-273)

MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases. / Alperin, Noam; Kadkhodayan, Y.; Varadarajalu, B.; Fisher, C.; Roitberg, B.

Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1 2001. p. 270-273.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Alperin, N, Kadkhodayan, Y, Varadarajalu, B, Fisher, C & Roitberg, B 2001, MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases. in Annual Reports of the Research Reactor Institute, Kyoto University. vol. 1, pp. 270-273, 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Istanbul, Turkey, 10/25/01.
Alperin N, Kadkhodayan Y, Varadarajalu B, Fisher C, Roitberg B. MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases. In Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1. 2001. p. 270-273
Alperin, Noam ; Kadkhodayan, Y. ; Varadarajalu, B. ; Fisher, C. ; Roitberg, B. / MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases. Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1 2001. pp. 270-273
@inproceedings{5b9b1557a13f4460bb8fc611a46e38f9,
title = "MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases",
abstract = "The volumes of the intracranial space and the craniospinal system as a whole change during the cardiac cycle. These volume changes are caused by the pulsatile arterial inflow to the cranium, venous outflow from the cranium, and cerebrospinal fluid (CSF) flow that oscillates back and forth between the cranium and the spinal canal. The volume changes can be measured accurately and reproducibly using a dynamic, motion-sensitive MRI technique [1]. It appears intuitive that the volume change of the entire craniospinal system (CSVC) should be greater than the intracranial volume change (ICVC). However, since they exhibit varying temporal information, CSVC can be smaller than ICVC. In the present study, these volume changes were measured in healthy humans and trauma cases. In the trauma cases, it was found that CSVC was smaller than ICVC. The cause was found to be increased pulsatility in the venous flow channels. It is suspected that the resulting relationship between ICVC and CSVC is related to the incidence of trauma, and perhaps CSVC being smaller than ICVC could serve as an indicator.",
keywords = "Arterial flow, Craniospinal system, Craniospinal volume change, CSF flow, Head trauma, Intracranial volume change, Modulation transfer function, Venous flow",
author = "Noam Alperin and Y. Kadkhodayan and B. Varadarajalu and C. Fisher and B. Roitberg",
year = "2001",
language = "English (US)",
volume = "1",
pages = "270--273",
booktitle = "Annual Reports of the Research Reactor Institute, Kyoto University",

}

TY - GEN

T1 - MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases

AU - Alperin, Noam

AU - Kadkhodayan, Y.

AU - Varadarajalu, B.

AU - Fisher, C.

AU - Roitberg, B.

PY - 2001

Y1 - 2001

N2 - The volumes of the intracranial space and the craniospinal system as a whole change during the cardiac cycle. These volume changes are caused by the pulsatile arterial inflow to the cranium, venous outflow from the cranium, and cerebrospinal fluid (CSF) flow that oscillates back and forth between the cranium and the spinal canal. The volume changes can be measured accurately and reproducibly using a dynamic, motion-sensitive MRI technique [1]. It appears intuitive that the volume change of the entire craniospinal system (CSVC) should be greater than the intracranial volume change (ICVC). However, since they exhibit varying temporal information, CSVC can be smaller than ICVC. In the present study, these volume changes were measured in healthy humans and trauma cases. In the trauma cases, it was found that CSVC was smaller than ICVC. The cause was found to be increased pulsatility in the venous flow channels. It is suspected that the resulting relationship between ICVC and CSVC is related to the incidence of trauma, and perhaps CSVC being smaller than ICVC could serve as an indicator.

AB - The volumes of the intracranial space and the craniospinal system as a whole change during the cardiac cycle. These volume changes are caused by the pulsatile arterial inflow to the cranium, venous outflow from the cranium, and cerebrospinal fluid (CSF) flow that oscillates back and forth between the cranium and the spinal canal. The volume changes can be measured accurately and reproducibly using a dynamic, motion-sensitive MRI technique [1]. It appears intuitive that the volume change of the entire craniospinal system (CSVC) should be greater than the intracranial volume change (ICVC). However, since they exhibit varying temporal information, CSVC can be smaller than ICVC. In the present study, these volume changes were measured in healthy humans and trauma cases. In the trauma cases, it was found that CSVC was smaller than ICVC. The cause was found to be increased pulsatility in the venous flow channels. It is suspected that the resulting relationship between ICVC and CSVC is related to the incidence of trauma, and perhaps CSVC being smaller than ICVC could serve as an indicator.

KW - Arterial flow

KW - Craniospinal system

KW - Craniospinal volume change

KW - CSF flow

KW - Head trauma

KW - Intracranial volume change

KW - Modulation transfer function

KW - Venous flow

UR - http://www.scopus.com/inward/record.url?scp=0035781772&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035781772&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0035781772

VL - 1

SP - 270

EP - 273

BT - Annual Reports of the Research Reactor Institute, Kyoto University

ER -