MRI measurements of craniospinal and intracranial volume change in healthy and head trauma cases

N. Alperin, Y. Kadkhodayan, B. Varadarajalu, C. Fisher, B. Roitberg

Research output: Contribution to journalConference article

Abstract

The volumes of the intracranial space and the craniospinal system as a whole change during the cardiac cycle. These volume changes are caused by the pulsatile arterial inflow to the cranium, venous outflow from the cranium, and cerebrospinal fluid (CSF) flow that oscillates back and forth between the cranium and the spinal canal. The volume changes can be measured accurately and reproducibly using a dynamic, motion-sensitive MRI technique [1]. It appears intuitive that the volume change of the entire craniospinal system (CSVC) should be greater than the intracranial volume change (ICVC). However, since they exhibit varying temporal information, CSVC can be smaller than ICVC. In the present study, these volume changes were measured in healthy humans and trauma cases. In the trauma cases, it was found that CSVC was smaller than ICVC. The cause was found to be increased pulsatility in the venous flow channels. It is suspected that the resulting relationship between ICVC and CSVC is related to the incidence of trauma, and perhaps CSVC being smaller than ICVC could serve as an indicator.

Original languageEnglish (US)
Pages (from-to)270-273
Number of pages4
JournalAnnual Reports of the Research Reactor Institute, Kyoto University
Volume1
StatePublished - Dec 1 2001
Externally publishedYes
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: Oct 25 2001Oct 28 2001

Keywords

  • Arterial flow
  • Craniospinal system
  • Craniospinal volume change
  • CSF flow
  • Head trauma
  • Intracranial volume change
  • Modulation transfer function
  • Venous flow

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Mechanical Engineering

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