MR fingerprinting using the quick echo splitting NMR imaging technique

Yun Jiang, Dan Ma, Renate Jerecic, Jeffrey Duerk, Nicole Seiberlich, Vikas Gulani, Mark A. Griswold

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Purpose: The purpose of the study is to develop a quantitative method for the relaxation properties with a reduced radio frequency (RF) power deposition by combining magnetic resonance fingerprinting (MRF) technique with quick echo splitting NMR imaging technique (QUEST). Methods: A QUEST-based MRF sequence was implemented to acquire high-order echoes by increasing the gaps between RF pulses. Bloch simulations were used to calculate a dictionary containing the range of physically plausible signal evolutions using a range of T1 and T2 values based on the pulse sequence. MRF-QUEST was evaluated by comparing to the results of spin-echo methods. The specific absorption rate (SAR) of MRF-QUEST was compared with the clinically available methods. Results: MRF-QUEST quantifies the relaxation properties with good accuracy at the estimated head SAR of 0.03 W/kg. T1 and T2 values estimated by MRF-QUEST are in good agreement with the traditional methods. Conclusions: The combination of the MRF and the QUEST provides an accurate quantification of T1 and T2 simultaneously with reduced RF power deposition. The resulting lower SAR may provide a new acquisition strategy for MRF when RF energy deposition is problematic. Magn Reson Med 77:979–988, 2017.

Original languageEnglish (US)
Pages (from-to)979-988
Number of pages10
JournalMagnetic Resonance in Medicine
Issue number3
StatePublished - Mar 1 2017
Externally publishedYes


  • MR fingerprinting
  • quantitative imaging
  • relaxation time
  • specific absorption rate

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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