Motility Disturbances in the Tube Versus Trabeculectomy Study During the First Year of Follow-up

Frederick M. Rauscher, Steven J Gedde, Joyce C. Schiffman, William J Feuer, Keith Barton, Richard K Lee

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Purpose: To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. Design: Multicenter randomized clinical trial. Methods: settings: Seventeen clinical centers. population: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy. interventions: 350-mm2 Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome measures: Preoperative and postoperative evaluation of ocular motility and diplopia. Results: Motility disturbances were detected in 55 patients (28%) at baseline. New-onset persistent diplopia was reported in 5 patients (5%) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9%) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). Conclusions: Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up.

Original languageEnglish
Pages (from-to)458-466
Number of pages9
JournalAmerican Journal of Ophthalmology
Volume147
Issue number3
DOIs
StatePublished - Mar 1 2009

Fingerprint

Trabeculectomy
Diplopia
Mitomycin
Glaucoma
Glaucoma Drainage Implants
Intraocular Pressure
Cataract
Randomized Controlled Trials
Outcome Assessment (Health Care)
Population

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Motility Disturbances in the Tube Versus Trabeculectomy Study During the First Year of Follow-up. / Rauscher, Frederick M.; Gedde, Steven J; Schiffman, Joyce C.; Feuer, William J; Barton, Keith; Lee, Richard K.

In: American Journal of Ophthalmology, Vol. 147, No. 3, 01.03.2009, p. 458-466.

Research output: Contribution to journalArticle

Rauscher, Frederick M. ; Gedde, Steven J ; Schiffman, Joyce C. ; Feuer, William J ; Barton, Keith ; Lee, Richard K. / Motility Disturbances in the Tube Versus Trabeculectomy Study During the First Year of Follow-up. In: American Journal of Ophthalmology. 2009 ; Vol. 147, No. 3. pp. 458-466.
@article{b4707e94069a4b299c46e86685d36968,
title = "Motility Disturbances in the Tube Versus Trabeculectomy Study During the First Year of Follow-up",
abstract = "Purpose: To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. Design: Multicenter randomized clinical trial. Methods: settings: Seventeen clinical centers. population: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy. interventions: 350-mm2 Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome measures: Preoperative and postoperative evaluation of ocular motility and diplopia. Results: Motility disturbances were detected in 55 patients (28{\%}) at baseline. New-onset persistent diplopia was reported in 5 patients (5{\%}) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9{\%}) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). Conclusions: Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up.",
author = "Rauscher, {Frederick M.} and Gedde, {Steven J} and Schiffman, {Joyce C.} and Feuer, {William J} and Keith Barton and Lee, {Richard K}",
year = "2009",
month = "3",
day = "1",
doi = "10.1016/j.ajo.2008.09.019",
language = "English",
volume = "147",
pages = "458--466",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "3",

}

TY - JOUR

T1 - Motility Disturbances in the Tube Versus Trabeculectomy Study During the First Year of Follow-up

AU - Rauscher, Frederick M.

AU - Gedde, Steven J

AU - Schiffman, Joyce C.

AU - Feuer, William J

AU - Barton, Keith

AU - Lee, Richard K

PY - 2009/3/1

Y1 - 2009/3/1

N2 - Purpose: To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. Design: Multicenter randomized clinical trial. Methods: settings: Seventeen clinical centers. population: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy. interventions: 350-mm2 Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome measures: Preoperative and postoperative evaluation of ocular motility and diplopia. Results: Motility disturbances were detected in 55 patients (28%) at baseline. New-onset persistent diplopia was reported in 5 patients (5%) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9%) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). Conclusions: Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up.

AB - Purpose: To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. Design: Multicenter randomized clinical trial. Methods: settings: Seventeen clinical centers. population: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy. interventions: 350-mm2 Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome measures: Preoperative and postoperative evaluation of ocular motility and diplopia. Results: Motility disturbances were detected in 55 patients (28%) at baseline. New-onset persistent diplopia was reported in 5 patients (5%) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9%) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). Conclusions: Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up.

UR - http://www.scopus.com/inward/record.url?scp=59749093993&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=59749093993&partnerID=8YFLogxK

U2 - 10.1016/j.ajo.2008.09.019

DO - 10.1016/j.ajo.2008.09.019

M3 - Article

C2 - 19038375

AN - SCOPUS:59749093993

VL - 147

SP - 458

EP - 466

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

IS - 3

ER -