Morphometric dual-energy X-ray absorptiometry of the spine: Report of a large series and correlation with axial bone mineral density

Antonio C. Bianco, Luiz F. Malvestiti, Cecilia H A Gouveia, Salim Wehba, Shlomo Lewin, Marilia M S Marone

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We studied vertebral morphometry and its relation to bone mineral density (BMD) in normal Brazilian women (n = 605). All women (age 22-97 years) were ambulatory and healthy. A lateral spine scan was done for morphometric X-ray absorptiometry using an imaging densitometer. In 429 of these women, BMD of the spine and proximal femur also were measured using dual-energy X-ray absorptiometry. All women were white with mean (± 1 SD) age of 53.7 (± 9.5) years. About 21% of the women over 50 years had a T score for spine BMD lower than -2.5 SD, and 7% had a femoral neck BMD below this osteoporosis threshold. Vertebral heights (anterior, H(A); middle, H(M); and posterior, Hp) and ratios (H(A)/H(P) and H(M)/H(p)) were assessed. There was no systematic difference between younger (20-49 years) and older (50+ years) women in heights or ratios. The vertebral heights were normalized for those observed in each individual case for the L2-L4 sequence. This normalization was adequate for all vertebral heights; the Z score averaged about +0.1. The average Z score for H(A)/H(P) was +0.01, but that for the H(M)/H(P) was -0.72, indicating that the latter ratio might differ from the reference population used (white American and European women). We observed a small positive correlation between vertebral heights and spine or femur BMD, but this was due entirely to the influence of body size on BMD. On a group basis, the H(M)/H(P) showed a significant association with axial BMD; the 1 SD difference between the lowest and highest quartile was associated with a difference of 8-15% (0.5-1.0 SD) in axial BMD.

Original languageEnglish
Pages (from-to)1605-1613
Number of pages9
JournalJournal of Bone and Mineral Research
Volume14
Issue number9
DOIs
StatePublished - Sep 13 1999

Fingerprint

Photon Absorptiometry
Bone Density
Spine
Femur
Femur Neck
Body Size
Osteoporosis
Population

ASJC Scopus subject areas

  • Surgery

Cite this

Morphometric dual-energy X-ray absorptiometry of the spine : Report of a large series and correlation with axial bone mineral density. / Bianco, Antonio C.; Malvestiti, Luiz F.; Gouveia, Cecilia H A; Wehba, Salim; Lewin, Shlomo; Marone, Marilia M S.

In: Journal of Bone and Mineral Research, Vol. 14, No. 9, 13.09.1999, p. 1605-1613.

Research output: Contribution to journalArticle

Bianco, Antonio C. ; Malvestiti, Luiz F. ; Gouveia, Cecilia H A ; Wehba, Salim ; Lewin, Shlomo ; Marone, Marilia M S. / Morphometric dual-energy X-ray absorptiometry of the spine : Report of a large series and correlation with axial bone mineral density. In: Journal of Bone and Mineral Research. 1999 ; Vol. 14, No. 9. pp. 1605-1613.
@article{2b1080b0d5f14d99a6d8381ad1d0aaf6,
title = "Morphometric dual-energy X-ray absorptiometry of the spine: Report of a large series and correlation with axial bone mineral density",
abstract = "We studied vertebral morphometry and its relation to bone mineral density (BMD) in normal Brazilian women (n = 605). All women (age 22-97 years) were ambulatory and healthy. A lateral spine scan was done for morphometric X-ray absorptiometry using an imaging densitometer. In 429 of these women, BMD of the spine and proximal femur also were measured using dual-energy X-ray absorptiometry. All women were white with mean (± 1 SD) age of 53.7 (± 9.5) years. About 21{\%} of the women over 50 years had a T score for spine BMD lower than -2.5 SD, and 7{\%} had a femoral neck BMD below this osteoporosis threshold. Vertebral heights (anterior, H(A); middle, H(M); and posterior, Hp) and ratios (H(A)/H(P) and H(M)/H(p)) were assessed. There was no systematic difference between younger (20-49 years) and older (50+ years) women in heights or ratios. The vertebral heights were normalized for those observed in each individual case for the L2-L4 sequence. This normalization was adequate for all vertebral heights; the Z score averaged about +0.1. The average Z score for H(A)/H(P) was +0.01, but that for the H(M)/H(P) was -0.72, indicating that the latter ratio might differ from the reference population used (white American and European women). We observed a small positive correlation between vertebral heights and spine or femur BMD, but this was due entirely to the influence of body size on BMD. On a group basis, the H(M)/H(P) showed a significant association with axial BMD; the 1 SD difference between the lowest and highest quartile was associated with a difference of 8-15{\%} (0.5-1.0 SD) in axial BMD.",
author = "Bianco, {Antonio C.} and Malvestiti, {Luiz F.} and Gouveia, {Cecilia H A} and Salim Wehba and Shlomo Lewin and Marone, {Marilia M S}",
year = "1999",
month = "9",
day = "13",
doi = "10.1359/jbmr.1999.14.9.1605",
language = "English",
volume = "14",
pages = "1605--1613",
journal = "Journal of Bone and Mineral Research",
issn = "0884-0431",
publisher = "Wiley-Blackwell",
number = "9",

}

TY - JOUR

T1 - Morphometric dual-energy X-ray absorptiometry of the spine

T2 - Report of a large series and correlation with axial bone mineral density

AU - Bianco, Antonio C.

AU - Malvestiti, Luiz F.

AU - Gouveia, Cecilia H A

AU - Wehba, Salim

AU - Lewin, Shlomo

AU - Marone, Marilia M S

PY - 1999/9/13

Y1 - 1999/9/13

N2 - We studied vertebral morphometry and its relation to bone mineral density (BMD) in normal Brazilian women (n = 605). All women (age 22-97 years) were ambulatory and healthy. A lateral spine scan was done for morphometric X-ray absorptiometry using an imaging densitometer. In 429 of these women, BMD of the spine and proximal femur also were measured using dual-energy X-ray absorptiometry. All women were white with mean (± 1 SD) age of 53.7 (± 9.5) years. About 21% of the women over 50 years had a T score for spine BMD lower than -2.5 SD, and 7% had a femoral neck BMD below this osteoporosis threshold. Vertebral heights (anterior, H(A); middle, H(M); and posterior, Hp) and ratios (H(A)/H(P) and H(M)/H(p)) were assessed. There was no systematic difference between younger (20-49 years) and older (50+ years) women in heights or ratios. The vertebral heights were normalized for those observed in each individual case for the L2-L4 sequence. This normalization was adequate for all vertebral heights; the Z score averaged about +0.1. The average Z score for H(A)/H(P) was +0.01, but that for the H(M)/H(P) was -0.72, indicating that the latter ratio might differ from the reference population used (white American and European women). We observed a small positive correlation between vertebral heights and spine or femur BMD, but this was due entirely to the influence of body size on BMD. On a group basis, the H(M)/H(P) showed a significant association with axial BMD; the 1 SD difference between the lowest and highest quartile was associated with a difference of 8-15% (0.5-1.0 SD) in axial BMD.

AB - We studied vertebral morphometry and its relation to bone mineral density (BMD) in normal Brazilian women (n = 605). All women (age 22-97 years) were ambulatory and healthy. A lateral spine scan was done for morphometric X-ray absorptiometry using an imaging densitometer. In 429 of these women, BMD of the spine and proximal femur also were measured using dual-energy X-ray absorptiometry. All women were white with mean (± 1 SD) age of 53.7 (± 9.5) years. About 21% of the women over 50 years had a T score for spine BMD lower than -2.5 SD, and 7% had a femoral neck BMD below this osteoporosis threshold. Vertebral heights (anterior, H(A); middle, H(M); and posterior, Hp) and ratios (H(A)/H(P) and H(M)/H(p)) were assessed. There was no systematic difference between younger (20-49 years) and older (50+ years) women in heights or ratios. The vertebral heights were normalized for those observed in each individual case for the L2-L4 sequence. This normalization was adequate for all vertebral heights; the Z score averaged about +0.1. The average Z score for H(A)/H(P) was +0.01, but that for the H(M)/H(P) was -0.72, indicating that the latter ratio might differ from the reference population used (white American and European women). We observed a small positive correlation between vertebral heights and spine or femur BMD, but this was due entirely to the influence of body size on BMD. On a group basis, the H(M)/H(P) showed a significant association with axial BMD; the 1 SD difference between the lowest and highest quartile was associated with a difference of 8-15% (0.5-1.0 SD) in axial BMD.

UR - http://www.scopus.com/inward/record.url?scp=0032880427&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032880427&partnerID=8YFLogxK

U2 - 10.1359/jbmr.1999.14.9.1605

DO - 10.1359/jbmr.1999.14.9.1605

M3 - Article

C2 - 10469290

AN - SCOPUS:0032880427

VL - 14

SP - 1605

EP - 1613

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

SN - 0884-0431

IS - 9

ER -