Morphologic effects of thio-TEPA on mouse urothelium

W. M. Murphy, M. S. Soloway, C. J. Lin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The urothelial changes induced by intravesical instillation of thio-TEPA into experimental animals were studied by cytologic, light microscopic, and electron microscopic techniques. Cells and tissue from treated and untreated groups were compared using a total of 54 discriminators. There were few consistent differences. Cells with marked nuclear atypia were not identified. The results indicate that thio-TEPA has little effect on non-diseased bladders. The atypical cells occasionally present in specimens from thio-TEPA treated bladders apparently do not emanate from normal urothelium.

Original languageEnglish
Pages (from-to)701-704
Number of pages4
JournalActa Cytologica
Volume21
Issue number5
StatePublished - Dec 1 1977
Externally publishedYes

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Triethylenephosphoramide
Urothelium
Urinary Bladder
Intravesical Administration
Electrons
Light

ASJC Scopus subject areas

  • Cell Biology
  • Anatomy
  • Histology

Cite this

Murphy, W. M., Soloway, M. S., & Lin, C. J. (1977). Morphologic effects of thio-TEPA on mouse urothelium. Acta Cytologica, 21(5), 701-704.

Morphologic effects of thio-TEPA on mouse urothelium. / Murphy, W. M.; Soloway, M. S.; Lin, C. J.

In: Acta Cytologica, Vol. 21, No. 5, 01.12.1977, p. 701-704.

Research output: Contribution to journalArticle

Murphy, WM, Soloway, MS & Lin, CJ 1977, 'Morphologic effects of thio-TEPA on mouse urothelium', Acta Cytologica, vol. 21, no. 5, pp. 701-704.
Murphy WM, Soloway MS, Lin CJ. Morphologic effects of thio-TEPA on mouse urothelium. Acta Cytologica. 1977 Dec 1;21(5):701-704.
Murphy, W. M. ; Soloway, M. S. ; Lin, C. J. / Morphologic effects of thio-TEPA on mouse urothelium. In: Acta Cytologica. 1977 ; Vol. 21, No. 5. pp. 701-704.
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