Mood disorders during pregnancy and lactation: Defining issues of exposure and treatment

Z. N. Stowe, K. Calhoun, C. Ramsey, N. Sadek, J. Newport

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Epidemiologic studies have consistently demonstrated a greater incidence of depressive disorders and anxiety among women. Many women experience these conditions during the reproductive years. The dramatic expanse of literature focusing on the use of medications often has failed to pay homage to the potential impact of the disorders. When considering the extant human and laboratory data on mental illness and stress during pregnancy and the postpartum period, it is evident that some degree of exposure (be it treatment or illness) always occurs. The primary goal of the risk-benefit assessment for the treatment of mental illness during these periods is to assist patients and their families in choosing the path of potential exposure that possesses the least risk for them. Once this decision is made, the goal is to limit the number of exposures for the fetus/neonate.

Original languageEnglish (US)
Pages (from-to)150-166
Number of pages17
JournalCNS spectrums
Issue number2
StatePublished - Jan 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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