Mood and hormone responses to psychological challenge in adolescent males with conduct problems

Keith McBurnett, Adrian Raine, Magda Stouthamer-Loeber, Rolf Loeber, Adarsh Kumar, Mahendra Kumar, Benjamin B. Lahey

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Background: Relations between stress hormones and antisocial behavior are understudied. Methods: A subsample (n = 335) of at-risk males recruited in first grade for a longitudinal study were recruited at approximately 16 years of age for a laboratory study, including two psychological challenges: describing their worst experience on videotape, and a task in which a loud tone could be avoided. Measures of affect, urine, and saliva were collected multiple times before and after challenges. Results: Negative affect increased following the worst-event challenge and decreased following the avoidance challenge. Mean conduct problems (CP) across ages 7-17 years were positively related to negative affect and inversely related to positive affect. CP were inversely related to post-challenge urinary epinephrine (E) levels when baseline E and potential confounds were controlled. Cortisol concentrations in saliva collected soon after the first challenge were positively related to CP in a post hoc subset of youths with extreme CP. Conclusions: Key findings A) associated persistent CP with more negative affectivity and less positive affectivity, B) replicated and extended prior findings of an inverse association of CP and urinary E, and C) suggested provocative hypotheses for future study relating CP, trauma history, trauma recall, and cortisol reactivity.

Original languageEnglish
Pages (from-to)1109-1116
Number of pages8
JournalBiological Psychiatry
Volume57
Issue number10
DOIs
StatePublished - May 15 2005

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Saliva
Hydrocortisone
Hormones
Psychology
Videotape Recording
Wounds and Injuries
Epinephrine
Longitudinal Studies
Urine

Keywords

  • Antisocial behavior
  • Conduct disorder
  • Cortisol
  • Epinephrine
  • HPA
  • mood

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

McBurnett, K., Raine, A., Stouthamer-Loeber, M., Loeber, R., Kumar, A., Kumar, M., & Lahey, B. B. (2005). Mood and hormone responses to psychological challenge in adolescent males with conduct problems. Biological Psychiatry, 57(10), 1109-1116. https://doi.org/10.1016/j.biopsych.2005.01.041

Mood and hormone responses to psychological challenge in adolescent males with conduct problems. / McBurnett, Keith; Raine, Adrian; Stouthamer-Loeber, Magda; Loeber, Rolf; Kumar, Adarsh; Kumar, Mahendra; Lahey, Benjamin B.

In: Biological Psychiatry, Vol. 57, No. 10, 15.05.2005, p. 1109-1116.

Research output: Contribution to journalArticle

McBurnett, K, Raine, A, Stouthamer-Loeber, M, Loeber, R, Kumar, A, Kumar, M & Lahey, BB 2005, 'Mood and hormone responses to psychological challenge in adolescent males with conduct problems', Biological Psychiatry, vol. 57, no. 10, pp. 1109-1116. https://doi.org/10.1016/j.biopsych.2005.01.041
McBurnett, Keith ; Raine, Adrian ; Stouthamer-Loeber, Magda ; Loeber, Rolf ; Kumar, Adarsh ; Kumar, Mahendra ; Lahey, Benjamin B. / Mood and hormone responses to psychological challenge in adolescent males with conduct problems. In: Biological Psychiatry. 2005 ; Vol. 57, No. 10. pp. 1109-1116.
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