Molecular biology of breast carcinoma

Dorraya El-Ashry, Marc E. Lippman

Research output: Contribution to journalArticle

25 Scopus citations


During the last several years basic research has resulted in the identification of many of the factors involved in signal transduction pathways, leading us to a greater understanding of the mechanisms of growth control in breast cancer cells. Many of these factors are the products of proto-oncogenes or suppressor genes. This review describes the role of some of these factors in breast cancer development, progression, and metastasis and discusses implications for future directions.

Original languageEnglish (US)
Pages (from-to)12-20
Number of pages9
JournalWorld Journal of Surgery
Issue number1
StatePublished - Jan 1 1994


ASJC Scopus subject areas

  • Surgery

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