MODULATION ET ANNIHILATION DES PACE-MAKERS VENTRICULAIRES PARASYSTOLIQUES

Translated title of the contribution: Modulation and suppression of parasystolic ventricular pacemakers

N. Saoudi, S. Kimura, W. Stafford, A. Castellanos, R. J. Myerburg

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Using a three part model of canine false tendon in which an inexcitable gap intervenes between the proximal and distal region of Purkinje fibers, Jalife and Moe recently individualized a biological model of parasystole and showed how the electrotonic depolarization can modulate, entrain or annihilate pacemaker activity. We report the ECG of 9 patients with parasystole (as assessed by the direct recording of ectopic cycle length) in which the early nonparasystolic beats delayed, whereas the late shortened the parasystolic cycle length. The phase response curve is specific for a given patient. In two cases a nonparasystolic impulse falling at a critical point in the ectopic cycle length was followed by the suppression of parasystolic activity on the surface EKG. The recently described phenomenon called pacemaker annihilation is discussed.

Translated title of the contributionModulation and suppression of parasystolic ventricular pacemakers
Original languageFrench
Pages (from-to)1495-1501
Number of pages7
JournalArchives des Maladies du Coeur et des Vaisseaux
Volume78
Issue number10
StatePublished - Dec 1 1985

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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