Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.
- Airway inflammation
- Animal models
- Mucus clearance
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine