Modeling of asthma, COPD and cystic fibrosis in sheep

William M. Abraham

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.

Original languageEnglish (US)
Pages (from-to)743-754
Number of pages12
JournalPulmonary Pharmacology and Therapeutics
Volume21
Issue number5
DOIs
StatePublished - Oct 1 2008

Keywords

  • Airway inflammation
  • Animal models
  • Bronchoconstriction
  • Mucus clearance

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Pharmacology

Fingerprint Dive into the research topics of 'Modeling of asthma, COPD and cystic fibrosis in sheep'. Together they form a unique fingerprint.

  • Cite this