Modeling of asthma, COPD and cystic fibrosis in sheep

William M. Abraham

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.

Original languageEnglish
Pages (from-to)743-754
Number of pages12
JournalPulmonary Pharmacology and Therapeutics
Volume21
Issue number5
DOIs
StatePublished - Oct 1 2008
Externally publishedYes

Fingerprint

Ascaris suum
Pulmonary diseases
Cystic Fibrosis
Chronic Obstructive Pulmonary Disease
Sheep
Asthma
Antigens
Allergic Rhinitis

Keywords

  • Airway inflammation
  • Animal models
  • Bronchoconstriction
  • Mucus clearance

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Pharmacology

Cite this

Modeling of asthma, COPD and cystic fibrosis in sheep. / Abraham, William M.

In: Pulmonary Pharmacology and Therapeutics, Vol. 21, No. 5, 01.10.2008, p. 743-754.

Research output: Contribution to journalArticle

Abraham, William M. / Modeling of asthma, COPD and cystic fibrosis in sheep. In: Pulmonary Pharmacology and Therapeutics. 2008 ; Vol. 21, No. 5. pp. 743-754.
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