Modeling of asthma, COPD and cystic fibrosis in sheep

William M. Abraham

doi:10.1016/j.pupt.2008.01.010

Modeling of asthma, COPD and cystic fibrosis in sheep

William M. Abraham

Medicine

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.

Original language	English (US)
Pages (from-to)	743-754
Number of pages	12
Journal	Pulmonary Pharmacology and Therapeutics
Volume	21
Issue number	5
DOIs	https://doi.org/10.1016/j.pupt.2008.01.010
State	Published - Oct 1 2008

Keywords

Airway inflammation
Animal models
Bronchoconstriction
Mucus clearance

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Pharmacology

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10.1016/j.pupt.2008.01.010

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title = "Modeling of asthma, COPD and cystic fibrosis in sheep",

abstract = "Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.",

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