Abstract
During the past year, a variety of methods have been developed with which to investigate the structures of large nucleic acids. Modeling techniques are assisting in the refinement of structures, particularly for large RNAs. Supercoiled DNA plasmids are being investigated using models that mimic the known elastic properties of the molecule. The level of detail in a particular modeling method must be appropriate to the question being posed.
Original language | English (US) |
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Pages (from-to) | 241-246 |
Number of pages | 6 |
Journal | Current Opinion in Structural Biology |
Volume | 3 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1993 |
Externally published | Yes |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology