Modal gating of NMDA receptors

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The decay time course of excitatory postsynaptic currents generated by slow glutamatergic synapses is determined by the single-channel kinetics of postsynaptic NMDA receptor channels. In a recent study, examination of these single-channel kinetics has revealed that NMDA receptors can enter into modal gating. Linear free-energy analysis suggests that the various modes arise from a common reaction mechanism, providing further insight into the gating underlying decay of the slow synaptic response.

Original languageEnglish
Pages (from-to)231-233
Number of pages3
JournalTrends in Neurosciences
Volume27
Issue number5
DOIs
StatePublished - May 1 2004

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N-Methyl-D-Aspartate Receptors
Excitatory Postsynaptic Potentials
Synapses

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Modal gating of NMDA receptors. / Magleby, Karl.

In: Trends in Neurosciences, Vol. 27, No. 5, 01.05.2004, p. 231-233.

Research output: Contribution to journalArticle

Magleby, Karl. / Modal gating of NMDA receptors. In: Trends in Neurosciences. 2004 ; Vol. 27, No. 5. pp. 231-233.
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