Mobility improvement of patients with peripheral visual field losses using novel see-through digital spectacles

Ahmed M. Sayed, Mohamed Abou Shousha, Islam Baharul Islam, Taher K. Eleiwa, Rashed Kashem, Mostafa Abdel-Mottaleb, Eyup Ozcan, Mohamed Tolba, Jane C. Cook, Richard K. Parrish

Research output: Contribution to journalArticlepeer-review


Purpose To evaluate see-through Augmented Reality Digital spectacles (AR DSpecs) for improving the mobility of patients with peripheral visual field (VF) losses when tested on a walking track. Design Prospective Case Series. Participants 21 patients with peripheral VF defects in both eyes, with the physical ability to walk without assistance. Methods We developed the AR DSpecs as a wearable VF aid with an augmented reality platform. Image remapping algorithms produced personalized visual augmentation in real time based on the measured binocular VF with the AR DSpecs calibration mode. We tested the device on a walking track to determine if patients could more accurately identify peripheral objects. Main outcome measures We analyzed walking track scores (number of recognized/avoided objects) and eye tracking data (six gaze parameters) to measure changes in the kinematic and eye scanning behaviors while walking, and assessed a possible placebo effect by deactivating the AR DSpecs remapping algorithms in random trials. Results Performance, judged by the object detection scores, improved with the AR DSpecs (P<0.001, Wilcoxon rank sum test) with an average improvement rate of 18.81%. Two gaze parameters improved with the activated algorithm (P<0.01, paired t-test), indicating a more directed gaze on the central path with less eye scanning. Determination of the binocular integrated VF with the DSpecs correlated with the integrated standard automated perimetry (R = 0.86, P<0.001), mean sensitivity difference 0.8 ± 2.25 dB (Bland-Altman). Conclusions AR DSpecs may improve walking maneuverability of patients with peripheral VF defects by enhancing detection of objects in a testing environment.

Original languageEnglish (US)
Article numbere0240509
JournalPloS one
Issue number10 October
StatePublished - Oct 2020

ASJC Scopus subject areas

  • General


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