Mitochondrial encephalomyopathies

S. DiMauro, E. Bonilla, A. Lombes, S. Shanske, C. Minetti, Carlos T Moraes

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The mitochondrial diseases present with great heterogeneity. They are often multisystemic and vary considerably in age at onset, distribution of weakness, severity, and course. Only nonthyroidal hypermetabolism has a distinctive clinical presentation. Therefore, attempts at classification have generated some controversy. This article discusses the general classification that takes into account genetic and biochemical features, which has resulted from the fast pace of biochemical and molecular genetic investigations.

Original languageEnglish
Pages (from-to)483-506
Number of pages24
JournalNeurologic Clinics
Volume8
Issue number3
StatePublished - Jan 1 1990
Externally publishedYes

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Mitochondrial Encephalomyopathies
Molecular Biology
Mitochondrial Diseases
Age of Onset

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

DiMauro, S., Bonilla, E., Lombes, A., Shanske, S., Minetti, C., & Moraes, C. T. (1990). Mitochondrial encephalomyopathies. Neurologic Clinics, 8(3), 483-506.

Mitochondrial encephalomyopathies. / DiMauro, S.; Bonilla, E.; Lombes, A.; Shanske, S.; Minetti, C.; Moraes, Carlos T.

In: Neurologic Clinics, Vol. 8, No. 3, 01.01.1990, p. 483-506.

Research output: Contribution to journalArticle

DiMauro, S, Bonilla, E, Lombes, A, Shanske, S, Minetti, C & Moraes, CT 1990, 'Mitochondrial encephalomyopathies', Neurologic Clinics, vol. 8, no. 3, pp. 483-506.
DiMauro S, Bonilla E, Lombes A, Shanske S, Minetti C, Moraes CT. Mitochondrial encephalomyopathies. Neurologic Clinics. 1990 Jan 1;8(3):483-506.
DiMauro, S. ; Bonilla, E. ; Lombes, A. ; Shanske, S. ; Minetti, C. ; Moraes, Carlos T. / Mitochondrial encephalomyopathies. In: Neurologic Clinics. 1990 ; Vol. 8, No. 3. pp. 483-506.
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