Abstract
We report a patient with mitochondrial DNA depletion, partial complex II and IV deficiencies, and 3-methylglutaconic aciduria. Complex II deficiency has not been previously observed in mitochondrial DNA depletion syndromes. The observation of 3-methyl-glutaconic and 3-methylglutaric acidurias may be a useful indicator of a defect in respiratory chain function caused by mitochondrial DNA depletion.
| Original language | English |
|---|---|
| Pages (from-to) | 136-138 |
| Number of pages | 3 |
| Journal | Journal of Child Neurology |
| Volume | 16 |
| Issue number | 2 |
| State | Published - May 12 2001 |
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
Cite this
Scaglia, F., Reid Sutton, V., Bodamer, O. A. F., Vogel, H., Shapira, S. K., Naviaux, R. K., & Vladutiu, G. D. (2001). Mitochondrial DNA depletion associated with partial complex II and IV deficiencies and 3-methylglutaconic aciduria. Journal of Child Neurology, 16(2), 136-138.