Mitochondrial DNA depletion associated with partial complex II and IV deficiencies and 3-methylglutaconic aciduria

F. Scaglia, V. Reid Sutton, O. A.F. Bodamer, H. Vogel, S. K. Shapira, R. K. Naviaux, G. D. Vladutiu

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

We report a patient with mitochondrial DNA depletion, partial complex II and IV deficiencies, and 3-methylglutaconic aciduria. Complex II deficiency has not been previously observed in mitochondrial DNA depletion syndromes. The observation of 3-methyl-glutaconic and 3-methylglutaric acidurias may be a useful indicator of a defect in respiratory chain function caused by mitochondrial DNA depletion.

Original languageEnglish (US)
Pages (from-to)136-138
Number of pages3
JournalJournal of child neurology
Volume16
Issue number2
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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    Scaglia, F., Reid Sutton, V., Bodamer, O. A. F., Vogel, H., Shapira, S. K., Naviaux, R. K., & Vladutiu, G. D. (2001). Mitochondrial DNA depletion associated with partial complex II and IV deficiencies and 3-methylglutaconic aciduria. Journal of child neurology, 16(2), 136-138. https://doi.org/10.1177/088307380101600214