Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: A pilot study

Jennifer L. Hundley, Gil Yosipovitch

Research output: Contribution to journalArticle

109 Scopus citations


Nocturnal pruritus is a significant problem for patients with inflammatory skin diseases and many systemic diseases. The oral therapies currently available have a limited effect. We present an open, uncontrolled pilot study of 3 patients with inflammatory skin diseases and severe nocturnal pruritus who underwent treatment with mirtazapine (Remeron), a noradrenergic and specific serotonergic antidepressant. Mirtazapine is a safe medication without serious side effects and may be an effective alternative for the treatment of nocturnal pruritus.

Original languageEnglish (US)
Pages (from-to)889-891
Number of pages3
JournalJournal of the American Academy of Dermatology
Issue number6
StatePublished - Jun 2004
Externally publishedYes


ASJC Scopus subject areas

  • Dermatology

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