Mirror syndrome associated with sacrococcygeal teratoma

A case report

Peter S. Finamore, Eftichia Kontopoulos, Mitchell Price, Gregg Giannina, John C. Smulian

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

BACKGROUND: Mirror syndrome is associated with both nonimmune and immune hydrops fetalis. The clinical manifestations are quite varied, and the pathophysiology is poorly understood. We describe a case of mirror syndrome associated with a fetus that had a rapidly growing sacrococcygeal teratoma (SCT) without overt hydrops. CASE: At 30 weeks' gestational age a fetus with SCT began to show early sonographic evidence of right heart failure, placentomegaly and polyhydramnios without overt fetal hydrops. Shortly after these findings were noted, the mother began to develop hypertension, epigastric pain, proteinuria and thrombocytopenia. These findings were all reversed after delivery of the fetus. Subsequent surgery on the infant was successful. CONCLUSION: Mirror syndrome has been linked with SCT and is usually associated with severe fetal hydropic changes. In our case the development of mirror syndrome preceded the manifestations of overt hydrops. Identification of early signs of fetal compromise or hydrops may help to predict patients who will develop mirror syndrome and improve outcomes with earlier intervention.

Original languageEnglish
Pages (from-to)225-227
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume52
Issue number3
StatePublished - Mar 1 2007

Fingerprint

Teratoma
Hydrops Fetalis
Edema
Fetus
Polyhydramnios
Proteinuria
Thrombocytopenia
Gestational Age
Heart Failure
Mothers
Hypertension
Pain

Keywords

  • Fetal hydrops
  • Mirror syndrome
  • Teratoma

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Finamore, P. S., Kontopoulos, E., Price, M., Giannina, G., & Smulian, J. C. (2007). Mirror syndrome associated with sacrococcygeal teratoma: A case report. Journal of Reproductive Medicine for the Obstetrician and Gynecologist, 52(3), 225-227.

Mirror syndrome associated with sacrococcygeal teratoma : A case report. / Finamore, Peter S.; Kontopoulos, Eftichia; Price, Mitchell; Giannina, Gregg; Smulian, John C.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 52, No. 3, 01.03.2007, p. 225-227.

Research output: Contribution to journalArticle

Finamore, PS, Kontopoulos, E, Price, M, Giannina, G & Smulian, JC 2007, 'Mirror syndrome associated with sacrococcygeal teratoma: A case report', Journal of Reproductive Medicine for the Obstetrician and Gynecologist, vol. 52, no. 3, pp. 225-227.
Finamore, Peter S. ; Kontopoulos, Eftichia ; Price, Mitchell ; Giannina, Gregg ; Smulian, John C. / Mirror syndrome associated with sacrococcygeal teratoma : A case report. In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 2007 ; Vol. 52, No. 3. pp. 225-227.
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