Miosis during vitreoretinal surgery

William E. Smiddy, Bert M. Glaser, Ronald G. Michels, Susan Vitale

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Maintenance of wide pupillary dilation during vitreoretinal surgery can be important in successful completion of the operation. This study identified factors associated with intraoperative miosis. Also, flubiprofen, a topically applied nonsteroidal anti-inflammatory agent, was evaluated for its efficacy in preventing intraoperative miosis in a prospective, randomized study of 99 consecutive patients. Factors associated with intraoperative miosis included duration of surgery greater than 90 minutes, preoperative afferent pupillary defect, and recent previous surgery. Preoperative treatment with flurbiprofen did not decrease the risk of intraoperative miosis.

Original languageEnglish (US)
Pages (from-to)42-46
Number of pages5
Issue number1
StatePublished - 1990


  • Flurbiprofen
  • Miosis
  • Mydriasis
  • Non-steroidal anti-inflammatory drugs
  • Prostaglandins
  • Pupillary dilation
  • Vitreoretinal surgery

ASJC Scopus subject areas

  • Ophthalmology


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